乳香液体粘合剂和液体粘合剂去除剂与葡萄糖酸氯己定酒精皮肤制剂的相容性评估。
Evaluation of Compatibility of a Gum Mastic Liquid Adhesive and Liquid Adhesive Remover With an Alcoholic Chlorhexidine Gluconate Skin Preparation.
作者信息
Ryder Marcia, Duley Collette
机构信息
Ryder Science, Inc, Brentwood, Tennessee (Dr Ryder); and BioScience Laboratories, Inc, Bozeman, Montana (Ms Duley). Marcia Ryder, PhD, MS, RN, of Ryder Science, is an independent collaborative researcher and consultant in medical biofilm-related infections. Her nursing practice includes critical care and nutrition support. She is a nationally and internationally recognized expert in the use and management of vascular access devices. Collette Duley, BS, has worked in the clinical laboratory for BioScience Laboratories for 10 years and as a principal investigator for more than 6 years. She has been an author on manuscripts and posters for various studies at numerous conferences.
出版信息
J Infus Nurs. 2017 Jul/Aug;40(4):245-252. doi: 10.1097/NAN.0000000000000230.
The compatibility of a 2% chlorhexidine gluconate/70% isopropyl alcohol (CHG/IPA) skin preparation with a gum mastic liquid adhesive (GMLA) and liquid adhesive remover (LAR) was assessed in healthy volunteers. Twenty subjects completed test material combination with microbial sampling at 3- and 7-day time points. Mean log10 reductions from baseline for normal flora were assessed. There was no significant difference in reduction of normal flora on skin prepped with CHG/IPA versus skin prepped with CHG/IPA followed by GMLA or LAR. The conclusion of the study was that the use of GMLA or LAR with CHG/IPA does not affect the antiseptic effectiveness of CHG/IPA.
在健康志愿者中评估了2%葡萄糖酸氯己定/70%异丙醇（CHG/IPA）皮肤准备液与乳香液体粘合剂（GMLA）和液体粘合剂去除剂（LAR）的兼容性。20名受试者在第3天和第7天时间点完成了测试材料组合及微生物采样。评估了正常菌群相对于基线的平均log10减少量。用CHG/IPA预处理的皮肤与先用CHG/IPA预处理再使用GMLA或LAR的皮肤在正常菌群减少方面没有显著差异。该研究的结论是，GMLA或LAR与CHG/IPA联合使用不会影响CHG/IPA的抗菌效果。
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