Cooijmans Kelly H M, Beijers Roseriet, Rovers Anne C, de Weerth Carolina
Department of Developmental Psychology, Behavioural Science Institute, Radboud University, P.O. Box 9140, 6500 HE, Nijmegen, The Netherlands.
BMC Pediatr. 2017 Jul 6;17(1):154. doi: 10.1186/s12887-017-0906-9.
Twenty-to-forty percent of women experience postpartum depressive symptoms, which can affect both the mother and infant. In preterm infants, daily skin-to-skin contact (SSC) between the mother and her infant has been shown to decrease maternal postpartum depressive symptoms. In full-term infants, only two studies investigated SSC effects on maternal depressive symptoms and found similar results. Research in preterm infants also showed that SSC improves other mental and physical health outcomes of the mother and the infant, and improves the quality of mother-infant relationship. This randomized controlled trial will investigate the effects of a SSC intervention on maternal postpartum depressive symptoms and additional outcomes in mothers and their full-term infants. Moreover, two potential underlying mechanisms for the relation between SSC and the maternal and infant outcomes will be examined, namely maternal oxytocin concentrations and infant intestinal microbiota.
METHODS/DESIGN: Design: A parallel-group randomized controlled trial.
116 mothers and their full-term infants.
Mothers in the SSC condition will be requested to provide daily at least one continuous hour of SSC to their infant. The intervention starts immediately after birth and lasts for 5 weeks. Mothers in the control condition will not be requested to provide SSC. Maternal and infant outcomes will be measured at 2 weeks, 5 weeks, 12 weeks and 1 year after birth.
maternal postpartum depressive symptoms. Secondary maternal outcomes: mental health (anxiety, stress, traumatic stress following child birth, sleep quality), physical health (physical recovery from the delivery, health, breastfeeding, physiological stress), mother-infant relationship (mother-infant bond, quality of maternal caregiving behavior). Secondary infant outcomes: behavior (fussing and crying, sleep quality), physical health (growth and health, physiological stress), general development (regulation capacities, social-emotional capacities, language, cognitive and motor capacities). Secondary underlying mechanisms: maternal oxytocin concentrations, infant intestinal microbiota.
As a simple and cost-effective intervention, SSC may benefit both the mother and her full-term infant in the short-and long-term. Additionally, if SSC is shown to be effective in low-risk mother-infant dyads, then thought could be given to developing programs in high-risk samples and using SSC in a preventive manner.
NTR5697 ; Registered on March 13, 2016.
20%至40%的女性会出现产后抑郁症状，这会对母亲和婴儿都产生影响。对于早产儿，母亲与婴儿之间的每日皮肤接触（SSC）已被证明可减轻母亲的产后抑郁症状。对于足月儿，仅有两项研究调查了SSC对母亲抑郁症状的影响并得出了类似结果。对早产儿的研究还表明，SSC可改善母亲和婴儿的其他身心健康结局，并提高母婴关系质量。这项随机对照试验将研究SSC干预对母亲产后抑郁症状以及母亲及其足月儿的其他结局的影响。此外，还将研究SSC与母婴结局之间关系的两个潜在潜在机制，即母亲的催产素浓度和婴儿的肠道微生物群。
方法/设计：设计：平行组随机对照试验。
116名母亲及其足月儿。
SSC组的母亲将被要求每天至少为其婴儿提供连续一小时的SSC接触。干预从出生后立即开始，持续5周。对照组的母亲不被要求提供SSC接触。母婴结局将在出生后2周、5周、12周和1年进行测量。
母亲产后抑郁症状。次要母亲结局：心理健康（焦虑、压力、产后创伤应激、睡眠质量）、身体健康（分娩后的身体恢复、健康、母乳喂养、生理应激）、母婴关系（母婴联结、母亲照顾行为质量）。次要婴儿结局：行为（烦躁哭闹、睡眠质量）、身体健康（生长与健康、生理应激）、总体发育（调节能力、社会情感能力、语言、认知和运动能力）。次要潜在机制：母亲催产素浓度、婴儿肠道微生物群。
作为一种简单且具有成本效益的干预措施，SSC可能在短期和长期内对母亲及其足月儿都有益处。此外，如果SSC在低风险母婴二元组中被证明有效，那么可以考虑在高风险样本中开展相关项目，并以预防性方式使用SSC。
NTR5697；于2016年3月13日注册。
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