Department of Developmental Psychology, Behavioural Science Institute, Radboud University, Thomas van Aquinostraat 4, 6525 GD, Nijmegen, The Netherlands.
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.
Sci Rep. 2022 Jun 17;12(1):10225. doi: 10.1038/s41598-022-14148-3.
This randomized controlled trial examined the effects of a daily hour of mother-infant skin-to-skin contact (SSC) during the first five postnatal weeks, compared to care-as-usual, on maternal depressive (primary outcome), anxiety, stress, fatigue, pain, and delivery-related post-traumatic stress symptoms (PTSS). Prenatal symptom severity and touch discomfort were examined as moderators. Mothers and full-term infants were randomly allocated to SSC or care-as-usual conditions and followed during the first postnatal year. For the total group (intention-to-treat analyses), care-as-usual mothers showed an increase of anxiety symptoms from week 2 to 12, while SSC mothers displayed a stability of anxiety symptoms. Also, care-as-usual mothers showed an initial decrease in fatigue followed by an increase, while SSC mothers showed a decrease from week 2 to 12. In per-protocol analyses, including only the SSC dyads who adhered to SSC guidelines, findings on anxiety, but not fatigue, were replicated. No SSC effects were found for depressive, stress, and pain symptoms. No moderator, dose-response, or 52-week follow-up effects were found. PTSS were low with little variation; consequently, analyses were discontinued. Daily SSC in healthy mother-infant dyads may reduce anxiety and fatigue symptoms, but not depressive, stress, and pain symptoms, during the early postpartum period. Replication studies are recommended.
这项随机对照试验研究了在产后前 5 周每天 1 小时母婴皮肤接触(SSC)与常规护理相比对产妇抑郁(主要结局)、焦虑、压力、疲劳、疼痛和与分娩相关的创伤后应激症状(PTSS)的影响。产前症状严重程度和触觉不适被作为调节因素进行了检查。母亲和足月婴儿被随机分配到 SSC 或常规护理条件下,并在产后第一年进行随访。对于总组(意向治疗分析),常规护理组的母亲在第 2 周到第 12 周焦虑症状增加,而 SSC 组的母亲焦虑症状稳定。此外,常规护理组的母亲在疲劳感开始下降后出现增加,而 SSC 组的母亲则从第 2 周到第 12 周疲劳感下降。在仅包括遵守 SSC 指南的 SSC 对子的方案分析中,焦虑症状得到了复制,但疲劳症状没有得到复制。SSC 对抑郁、压力和疼痛症状没有影响。没有发现调节因素、剂量反应或 52 周随访的影响。PTSS 较低且变化不大;因此,分析被停止。在健康母婴对子中,每日 SSC 可能会在产后早期减少焦虑和疲劳症状,但不会减轻抑郁、压力和疼痛症状。建议进行复制研究。