Heard Rachel S M, Ramsay George, Hildebrand Diane R
Department of General Surgery, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK.
Department of Vascular Surgery, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK.
Surgeon. 2017 Dec;15(6):366-371. doi: 10.1016/j.surge.2017.06.001. Epub 2017 Jul 3.
Sarcopaenia, or decreased muscle mass, has been the subject of a large quantity of recent literature in both medical and surgical disciplines. It has been shown, as outlined below, to be of great prognostic importance, and also may be used in certain circumstances to guide treatment. The greatest volume of research into this topic is in oncological surgical populations, in whom the prevalence of sarcopaenia has been shown to be high. However it is being increasingly studied in other patient groups. Interest in using sarcopaenia as an objective and potentially modifiable marker of frailty is increasing, especially with regards to pre-operative risk stratification and amelioration. In this review we consider the current literature regarding the cause and effect of sarcopaenia, the methods by which it may be identified and the potential ways in which it may be treated, in the interest of improving outcomes for surgical patients.
肌肉减少症，即肌肉量减少，已成为近期医学和外科学科大量文献的主题。如下所述，它已被证明具有重要的预后意义，并且在某些情况下也可用于指导治疗。对这一主题的研究最多的是肿瘤外科人群，其中肌肉减少症的患病率已被证明很高。然而，它在其他患者群体中的研究也越来越多。将肌肉减少症作为虚弱的客观且可能可改变的标志物的兴趣正在增加，特别是在术前风险分层和改善方面。在本综述中，为了改善外科患者的治疗效果，我们考虑了有关肌肉减少症的因果关系、识别方法以及可能的治疗方法的当前文献。
