Fuchsluger T A, Kruse F E, Geerling G
Klinik für Augenheilkunde, Universitätsklinik Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland.
Klinik für Augenheilkunde, Universitätsklinik Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Deutschland.
Ophthalmologe. 2017 Aug;114(8):688-692. doi: 10.1007/s00347-017-0524-9.
In view of the very low proliferation rate and functional importance of the corneal endothelium in maintaining corneal transparency, safeguarding the integrity of this monolayer plays a central role in posterior lamellar corneal transplantation. Several critical endothelial procedural stages are necessary to carry out such a transplantation.
This article presents various preparatory and operative approaches for carrying out the necessary and critical stages within the framework of posterior lamellar corneal transplantation and concentrates on the question of optimization.
A review of our own studies and studies of other groups is presented.
For the performance of critical endothelial procedural steps, a variety of approaches are available. These range from preparation and insertion of the transplant, through the manipulation during centralization up to the effects of postoperative air or gas bubble tamponade.
Because endothelial damage can permanently impair the integrity of lamellar transplants, a minimal handling and no touch policy should be strived for in all critical procedures. Long-term data on the follow-up course will show which of the procedures favored by various authors lead to the best postoperative results.
鉴于角膜内皮细胞的增殖率极低且在维持角膜透明度方面具有重要功能，保护这一单细胞层的完整性在角膜后板层移植中起着核心作用。进行此类移植需要几个关键的内皮细胞操作阶段。
本文介绍了在角膜后板层移植框架内进行必要且关键阶段的各种准备和手术方法，并着重探讨优化问题。
介绍了我们自己的研究以及其他团队的研究。
对于关键的内皮细胞操作步骤，有多种方法可供选择。这些方法涵盖从移植片的制备和植入，到在对合过程中的操作，直至术后空气或气泡填塞的效果。
由于内皮细胞损伤会永久性损害板层移植片的完整性，在所有关键操作中应努力遵循最小化操作和无接触原则。关于随访过程的长期数据将表明各位作者所青睐的哪些操作能带来最佳的术后效果。
