Cao Xinhua, Xu Xiaoyin, Drubach Laura, Fahey Frederic H
Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave., Boston, MA, 02115, USA.
Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Pediatr Radiol. 2017 Nov;47(12):1599-1607. doi: 10.1007/s00247-017-3917-7. Epub 2017 Jul 6.
When performing dynamic gastric emptying scintigraphy with continuous acquisition in children, a single posterior view acquisition is preferred because it allows the young patient to more easily interact with a parent or technologist even though this method tends toward overestimating gastric emptying.
The objective of our study was to develop a new attenuation correction (AC) method to improve the accuracy of the time activity curve and the measurement of residual gastric emptying from 1-h posterior images of gastric emptying scintigraphy with continuous acquisition.
We developed a frame-count-based AC for gastric emptying scintigraphy from the posterior view (posterior AC method). We retrospectively reviewed 122 gastric emptying studies performed in children using conjugated posterior and anterior views, and evaluated the statistical differences between posterior only (without AC) and posterior AC using the geometric mean method as a reference standard.
The residual values obtained using posterior AC were not significantly different (P=0.813) compared to those using the geometric mean while the values using the posterior only were significantly different (P<0.001) from the geometric mean.
The proposed method can replace the geometric mean method to estimate gastric emptying residual fraction using patient-friendly posterior view without a significant difference in 1-h gastric emptying scintigraphy with continuous acquisition.
在对儿童进行连续采集的动态胃排空闪烁扫描时，单后位视图采集更受青睐，因为这能让年幼患者更轻松地与家长或技术人员互动，尽管这种方法往往会高估胃排空情况。
我们研究的目的是开发一种新的衰减校正（AC）方法，以提高连续采集的胃排空闪烁扫描1小时后位图像的时间-活性曲线及残余胃排空测量的准确性。
我们开发了一种基于帧数的后位胃排空闪烁扫描AC方法（后位AC方法）。我们回顾性分析了122例儿童胃排空研究，这些研究采用了共轭后位和前位视图，并以几何平均法作为参考标准，评估仅后位（无AC）和后位AC之间的统计学差异。
与使用几何平均法相比，使用后位AC获得的残余值无显著差异（P = 0.813），而仅使用后位获得的值与几何平均法有显著差异（P < 0.001）。
在连续采集的1小时胃排空闪烁扫描中，可以用所提出的方法替代几何平均法，以使用对患者友好的后位视图来估计胃排空残余分数，且无显著差异。
