Department of Radiology, Nuclear Medicine, Temple University Hospital and School of Medicine, Philadelphia, PA 19140, USA.
Semin Nucl Med. 2012 Mar;42(2):101-12. doi: 10.1053/j.semnuclmed.2011.10.001.
For many years, gastric emptying (GE) studies were performed using various local protocols and different radiolabeled meals. This lack of standardization and normal values made the test results unreliable and difficult to compare from one site to another. A recent consensus has been published that now provides guidance and standardization on how to perform a radiolabeled solid-meal GE study. It is widely recognized, however, that simple measurement of total GE of a solid meal often does not provide an answer to the etiology of symptoms for a large number of patients who present with functional dyspepsia. Advances in our understanding of the different roles of the fundus and antrum and their complex interaction with the proximal small bowel and central nervous system have led to the development of new methods to study gastric motility. This review describes how a more comprehensive approach to studying GE is needed and how this will lead to better diagnosis and treatment for patients referred for GE studies.
多年来，胃排空（GE）研究使用各种局部方案和不同的放射性标记餐进行。这种缺乏标准化和正常值的情况使得测试结果不可靠，并且难以在不同地点之间进行比较。最近发表了一项共识，为如何进行放射性标记固体餐 GE 研究提供了指导和标准化。然而，人们普遍认识到，简单测量固体餐的总 GE 通常不能为大量出现功能性消化不良症状的患者提供病因的答案。我们对胃底和胃窦的不同作用及其与近端小肠和中枢神经系统的复杂相互作用的理解的进步，导致了研究胃动力的新方法的发展。本综述描述了为什么需要更全面的方法来研究 GE，以及这将如何为接受 GE 研究的患者带来更好的诊断和治疗。
