来自海葵克氏海葵的一种溶细胞毒素的特性。

Properties of a cytolytic toxin from the sea anemone, Stoichactis kenti.

作者信息

Bernheimer A W, Lai C Y

出版信息

Toxicon. 1985;23(5):791-9. doi: 10.1016/0041-0101(85)90010-8.

Abstract

A cytolytic toxin (kentin) from the Indo-Pacific sea anemone, Stoichactis kenti, was purified to near homogeneity. The toxin is a basic polypeptide of molecular weight approximately 18,000. It broadly resembles cytotoxins from Stoichactis helianthus (helianthin), as well as similar toxins from a number of other anemones, namely Condylactis, Epiactis, Actinia, Pseudactinia, Tealia, Anthopleura, Radianthus and Gyrostoma. The amino acid composition of kentin shows considerable resemblance to that of helianthin, but there are also several significant differences. Neutralization tests indicate that kentin and helianthin are immunologically related but distinguishable. In contrast, no immunological relatedness was found between helianthin and cytolytic toxins from Condylactis gigantea and Epiactis prolifera.

摘要

从印度-太平洋海葵克氏艾氏海葵（Stoichactis kenti）中纯化出一种溶细胞毒素（肯廷毒素），纯度接近均一。该毒素是一种分子量约为18,000的碱性多肽。它与来自太阳海葵（Stoichactis helianthus）的细胞毒素（海葵毒素）以及其他一些海葵（即康氏海葵、艾氏海葵、红海葵、拟红海葵、拟菊海葵、侧花海葵、辐射海葵和陀螺海葵）的类似毒素有广泛相似性。肯廷毒素的氨基酸组成与海葵毒素有相当大的相似性，但也存在一些显著差异。中和试验表明，肯廷毒素和海葵毒素在免疫上相关但可区分。相比之下，未发现海葵毒素与来自巨大康氏海葵和增殖艾氏海葵的溶细胞毒素之间存在免疫相关性。