Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology Gokiso, Showa-ku, Nagoya 466-8555, Japan.
Department of Life Science and Applied Chemistry, Nagoya Institute of Technology Gokiso, Showa-ku, Nagoya 466-8555, Japan.
Molecules. 2017 Jul 7;22(7):1130. doi: 10.3390/molecules22071130.
We disclose herein the perfluoroalkylation of alkenes catalyzed by trifluoroethoxy-coated zinc phthalocyanine under irradiation of visible light. Perfluoroalkyl iodides were nicely incorporated into unsaturated substrates, including alkyne, to provide perfluoroalkyl and iodide adducts in moderate to good yields. Trifluoromethylation is also possible by trifluoromethyl iodide under the same reaction conditions. The mechanistic study is discussed.
我们在此公开了三氟乙氧基包覆锌酞菁在可见光照射下催化烯烃的全氟烷基化反应。全氟碘代烷烃很好地与不饱和底物（包括炔烃）加成，以中等至良好的收率得到全氟烷基和碘化物加合物。在相同的反应条件下，三氟甲基碘化物也可以进行三氟甲基化。讨论了反应机理。
