Department of Internal Medicine-Geriatrics, Saint Louis University School of Medicine, 1402 South Grand Boulevard, Suite M238, St Louis, MO 63104, USA.
Clin Geriatr Med. 2017 Aug;33(3):325-337. doi: 10.1016/j.cger.2017.02.005. Epub 2017 May 17.
Mild cognitive impairment (MCI) occurs along a continuum from normal cognition to dementia. A roadblock to earlier diagnosis and potential treatment is the lack of consistency with screening for MCI. Universal screening would be ideal, but is limited. Once a diagnosis of MCI is made, it is important for the clinician to evaluate for reversible causes. At present time, there are no pharmacologic treatments proven to slow or cure progression of MCI to dementia; nonetheless, there is evidence that lifestyle modifications including diet, exercise, and cognitive stimulation may be effective.
轻度认知障碍(MCI)是从正常认知到痴呆的连续过程中的一个环节。早期诊断和潜在治疗的一个障碍是缺乏 MCI 筛查的一致性。普遍筛查是理想的,但受到限制。一旦做出 MCI 的诊断,临床医生评估可逆转的病因非常重要。目前,还没有被证实可以减缓或治愈 MCI 向痴呆发展的药物治疗方法;尽管如此,有证据表明,生活方式的改变,包括饮食、运动和认知刺激,可能是有效的。