Tumin Dmitry, Li Susan S, Nandi Deipanjan, Gajarski Robert J, McKee Christopher, Tobias Joseph D, Hayes Don
Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH; Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH.
Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH; Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH.
J Pediatr. 2017 Sep;188:82-86. doi: 10.1016/j.jpeds.2017.06.014. Epub 2017 Jul 6.
To describe the change in health insurance after heart transplantation among adolescents, and characterize the implications of this change for long-term transplant outcomes.
Patients age 15-18 years receiving first-time heart transplantation between 1999 and 2011 were identified in the United Network for Organ Sharing registry and included in the analysis if they survived at least 5 years. The primary exposure was change or continuity of health insurance coverage between the time of transplant and the 5-year follow-up. Cox proportional hazards models were used to determine the association between insurance status change and long-term (>5 years) patient and graft survival.
The analysis included 366 patients (age 16 ± 1 years at transplant), of whom 205 (56%) had continuous private insurance; 96 (26%) had continuous public insurance; and 65 (18%) had a change in insurance status. In stepwise multivariable Cox regression, change in insurance status was associated with greater mortality hazard, compared with continuous private insurance (hazard ratio = 1.9; 95% CI: 1.1, 3.2; P = .016), whereas long-term patient and graft survival did not differ between patients with continuous public and continuous private insurance.
Continuity of insurance coverage is associated with improved long-term clinical outcomes among adolescent heart transplant recipients who survive into adulthood.
描述青少年心脏移植后医疗保险的变化,并阐述这种变化对长期移植结局的影响。
在器官共享联合网络登记处识别出1999年至2011年间接受首次心脏移植的15 - 18岁患者,若他们存活至少5年则纳入分析。主要暴露因素是移植时到5年随访期间医疗保险覆盖情况的变化或连续性。采用Cox比例风险模型确定保险状态变化与长期(>5年)患者及移植物存活之间的关联。
分析纳入366例患者(移植时年龄16±1岁),其中205例(56%)拥有持续的私人保险;96例(26%)拥有持续的公共保险;65例(18%)保险状态发生了变化。在逐步多变量Cox回归分析中,与持续拥有私人保险相比,保险状态变化与更高的死亡风险相关(风险比 = 1.9;95%置信区间:1.1, 3.2;P = 0.016),而持续拥有公共保险和持续拥有私人保险的患者之间长期患者及移植物存活情况并无差异。
对于存活至成年期的青少年心脏移植受者,保险覆盖的连续性与改善长期临床结局相关。