Centro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC) Avenida dos Estados, 5001 - Bangú, Santo André - SP, 09210-580, Brazil.
Eur J Dermatol. 2017 Jun 1;27(S1):4-7. doi: 10.1684/ejd.2017.3038.
The human body is inhabited by complex microbial communities, which positively impact different aspects of our health, and might also be related to the development of diseases. Progress in technologies, particularly sequencing methods and bioinformatics tools, has been crucial for the advances in this field. Microbial communities from skin can modulate immune response and protect the host against pathogens, and there are also data supporting their association with several skin conditions; including dandruff and seborrheic dermatitis. For decades, they have been thought to be related to Malassezia yeasts; however, the microbial role has not been elucidated, and their etiology remains poorly understood. This review discusses the recent findings in dandruff and seborrheic dermatitis and their relation to the skin microbiota. Data provided new perceptions to aid in the understanding of these skin disorders, broadening our view of their etiology and the possible roles of microbial communities in symptom development.
人体中栖息着复杂的微生物群落，这些微生物对我们的健康的多个方面都有着积极影响，而且可能与疾病的发展有关。技术的进步，特别是测序方法和生物信息学工具的进步，对该领域的发展至关重要。皮肤微生物群落可以调节免疫反应并保护宿主免受病原体的侵害，而且还有数据支持它们与几种皮肤状况有关，包括头皮屑和脂溢性皮炎。数十年来，人们一直认为它们与马拉色菌酵母有关；然而，微生物的作用尚未阐明，其病因仍知之甚少。本综述讨论了头皮屑和脂溢性皮炎的最新发现及其与皮肤微生物组的关系。提供的数据为帮助我们理解这些皮肤疾病提供了新的认识，拓宽了我们对其病因的认识以及微生物群落在症状发展中的可能作用。
