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头皮屑和脂溢性皮炎中人类头皮微生物组网络的崩溃。

Collapse of human scalp microbiome network in dandruff and seborrhoeic dermatitis.

机构信息

Skin Research Institute, Amorepacific Corporation R&D Center, Yongin, Korea.

Department of Systems Biotechnology, Chung-Ang University, Anseong, Korea.

出版信息

Exp Dermatol. 2017 Sep;26(9):835-838. doi: 10.1111/exd.13293. Epub 2017 Apr 11.

DOI:10.1111/exd.13293
PMID:28094891
Abstract

We investigate the relationship between scalp microbiota and dandruff/seborrhoeic dermatitis (D/SD), an unpleasant scalp disorder common in human populations. Bacterial and fungal community analyses on scalp of 102 Korean were performed by next-generation sequencing. Overall scalp microbiome composition significantly differed between normal and disease groups, and especially co-occurrence network of dominant members was breakdown in disease groups. These findings will provide novel insights into shifts of microbial community relevant to D/SD.

摘要

我们研究了头皮微生物群与头皮屑/脂溢性皮炎(D/SD)之间的关系,D/SD 是一种常见于人类的令人不适的头皮疾病。通过下一代测序对 102 名韩国人的头皮进行了细菌和真菌群落分析。正常组和疾病组的整体头皮微生物组组成存在显著差异,特别是疾病组中优势成员的共生网络发生了破裂。这些发现将为与 D/SD 相关的微生物群落变化提供新的见解。

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