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炎症性肠病患者结直肠癌筛查和监测的内镜检查建议:一般建议综述

Endoscopic recommendations for colorectal cancer screening and surveillance in patients with inflammatory bowel disease: Review of general recommendations.

作者信息

Huguet Jose María, Suárez Patricia, Ferrer-Barceló Luis, Ruiz Lucía, Monzó Ana, Durá Ana Belén, Sempere Javier

机构信息

Jose María Huguet, Patricia Suárez, Luis Ferrer-Barceló, Lucía Ruiz, Ana Monzó, Ana Belén Durá, Javier Sempere, Digestive Disease Department, General University Hospital of Valencia, 46014 Valencia, Spain.

出版信息

World J Gastrointest Endosc. 2017 Jun 16;9(6):255-262. doi: 10.4253/wjge.v9.i6.255.

Abstract

Screening for colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD) is recommended by all scientific societies. However, there are differences in the recommendations they make regarding screening and surveillance. We address a series of questions that come up in the daily clinical practice of a physician. The first two questions that are raised are: (1) Who should be offered screening for CRC? and (2) When should the first colonoscopy be performed? The next step is to decide who should undergo endoscopic surveillance and at what intervals they should be performed. Chromoendoscopy is emerging as the recommended endoscopic technique for screening and surveillance. The terminology for describing lesions detected with endoscopy is also changing. The management of visible lesions or non-visible dysplasia is also a motive for the review. We end the review by addressing the follow-up for endoscopically resected lesions. These questions often cannot be answered easily due to the varying degrees of evidence available; therefore, we have made some general recommendations based on those made by the various guidelines and consensuses. The first screening colonoscopy should be offered 8 years after a IBD diagnosis and we recommend that patients be stratified according to the individual risk for each for endoscopic surveillance intervals.

摘要

所有科学学会都建议对炎症性肠病(IBD)患者进行结直肠癌(CRC)筛查。然而,他们在筛查和监测建议方面存在差异。我们探讨了医生日常临床实践中出现的一系列问题。首先提出的两个问题是:(1)哪些人应该接受CRC筛查?(2)首次结肠镜检查应在何时进行?下一步是决定谁应该接受内镜监测以及监测的间隔时间。染色内镜正成为推荐用于筛查和监测的内镜技术。描述内镜检查发现病变的术语也在变化。对可见病变或不可见发育异常的处理也是本次综述的一个动因。我们通过讨论内镜切除病变的随访来结束本次综述。由于现有证据程度不同,这些问题往往不易回答;因此,我们根据各种指南和共识提出了一些一般性建议。首次筛查结肠镜检查应在IBD诊断后8年进行,并且我们建议根据个体风险对患者进行分层,以确定各自的内镜监测间隔时间。

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