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适量食用非营养性甜味剂对大鼠葡萄糖耐量和身体成分的影响。

The effect of moderate consumption of non-nutritive sweeteners on glucose tolerance and body composition in rats.

机构信息

Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, 4505 S. Maryland Parkway, Las Vegas, NV 89154-3034, USA.

出版信息

Appl Physiol Nutr Metab. 2017 Nov;42(11):1225-1227. doi: 10.1139/apnm-2017-0120. Epub 2017 Jul 10.

DOI:10.1139/apnm-2017-0120
PMID:28692807
Abstract

Glucose tolerance and body composition were determined in male rats given non-nutritive sweeteners (NNS) (aspartame or sucralose) in drinking water. Areas under the curve for glucose and insulin with NNS did not differ from control. NNS treatment had no effect on weight gain or percent body fat. Epididymal fat pad mass was higher with aspartame and the ratio of trunk to total fat was less with sucralose versus control, suggesting that NNS consumption altered body fat distribution.

摘要

在给予雄性大鼠非营养性甜味剂(阿斯巴甜或三氯蔗糖)饮用水的实验中,测定了其葡萄糖耐量和身体成分。非营养性甜味剂组的葡萄糖和胰岛素曲线下面积与对照组无差异。非营养性甜味剂处理对体重增加或体脂肪百分率没有影响。与对照组相比,阿斯巴甜组附睾脂肪垫质量更高,而三氯蔗糖组躯干与总脂肪的比例更低,这表明非营养性甜味剂的摄入改变了体脂肪分布。

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