肺血管肉瘤的临床表现和诊断方法：系统评价方案。
Clinical manifestations and diagnostic methods in pulmonary angiosarcoma: protocol for a scoping review.
机构信息
Cumming School of Medicine, University of Calgary, Foothills Medical Centre, Room 933, North Tower, 1403-29 Street NW, Calgary, AB, T2N 2T9, Canada.
University of British Columbia, 7th Floor, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada.
出版信息
Syst Rev. 2017 Jul 10;6(1):136. doi: 10.1186/s13643-017-0531-6.
BACKGROUND
Angiosarcoma involving the lung can represent either primary or metastatic malignancy. Due to the rarity of this condition, knowledge surrounding the natural history and clinical presentation is scarce. The aim of this scoping review is to summarize the existing literature on pulmonary angiosarcoma, particularly as it pertains to the clinical presentation and ancillary tests used for diagnosis in addition to histopathology.
METHODS
We will conduct a systematic search using Ovid MEDLINE and EMBASE electronic databases. Two investigators will independently screen identified titles and abstracts to select articles reporting on pulmonary angiosarcoma. The data will be summarized in a narrative fashion and organized according to aspects of epidemiology, risk factors, clinical presentation, diagnostic methods, and treatment.
DISCUSSION
Scoping reviews are increasingly used to synthesize the evidence on a particular topic, to identify gaps in the literature, and to determine if future systematic reviews are feasible. In order to improve the care of patients with angiosarcoma, earlier recognition and diagnosis is required. This review will be valuable for highlighting the range of clinical presentations and the role of imaging and other diagnostic tools in the diagnosis of metastatic and primary pulmonary angiosarcoma.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO registration: CRD42017059052.
背景
肺血管肉瘤既可表现为原发性，也可表现为转移性恶性肿瘤。由于这种疾病较为罕见，因此对于其自然病史和临床表现的了解也较为缺乏。本次范围界定综述旨在对肺血管肉瘤的现有文献进行总结，尤其是涉及到临床表现以及辅助诊断检查（除了组织病理学检查以外）的内容。
方法
我们将使用 Ovid MEDLINE 和 EMBASE 电子数据库进行系统检索。两名调查员将独立筛选确定的标题和摘要，以选择报告肺血管肉瘤的文章。将按照流行病学、危险因素、临床表现、诊断方法和治疗等方面的内容以叙述的方式对数据进行总结。
讨论
范围界定综述越来越多地用于综合特定主题的证据，以确定文献中的空白，并确定未来进行系统综述是否可行。为了改善血管肉瘤患者的护理，需要更早地识别和诊断。该综述将有助于突出各种临床表现，以及影像学和其他诊断工具在诊断转移性和原发性肺血管肉瘤中的作用。
系统综述注册
PROSPERO 注册：CRD42017059052。
Zotero 插件