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酷似脑肿瘤的神经白塞病:一例报告。

Neuro-Behçet disease mimicking brain tumor: A case report.

作者信息

Tramontini Pedro L, Finkelsztejn Alessandro, Duarte Juliana Á, Santos Guilherme T, Roesler Rafael, Isolan Gustavo R

机构信息

Neurosurgery Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.

Neurology Department, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.

出版信息

Surg Neurol Int. 2017 Jun 5;8:97. doi: 10.4103/sni.sni_3_17. eCollection 2017.

DOI:10.4103/sni.sni_3_17
PMID:28695044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5473079/
Abstract

BACKGROUND

Behçet's disease (BD) is an inflammatory multisystem disease with unknown etiology, and consists of a TRIAD comprising recurrent oral ulcers, genital ulcers, and uveitis. In some cases, the disease affects the central nervous system, called Neuro-Behçet Disease (NBD). Few cases of NBD simulating a brain tumor have been previously reported.

CASE DESCRIPTION

Here, we describe the case of a 46-year-old male patient with a previous diagnosis of brain tumor who was later diagnosed for BD.

CONCLUSION

This case highlights the importance of differential diagnosis of lesions with tumoral features. Checking for the possibility of NBD may help avoiding biopsy in these types of cases.

摘要

背景

白塞病(BD)是一种病因不明的炎症性多系统疾病,由复发性口腔溃疡、生殖器溃疡和葡萄膜炎组成的三联征构成。在某些情况下,该疾病会影响中枢神经系统,称为神经白塞病(NBD)。此前鲜有NBD模拟脑肿瘤的病例报道。

病例描述

在此,我们描述一例先前诊断为脑肿瘤,后来被诊断为BD的46岁男性患者的病例。

结论

该病例突出了对具有肿瘤特征的病变进行鉴别诊断的重要性。检查NBD的可能性可能有助于避免在这类病例中进行活检。

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引用本文的文献

1
Case report: A case of neuro-Behçet's syndrome presenting as brain stem mass lesions.病例报告:一例表现为脑干肿块病变的神经白塞病。
Front Neurol. 2023 Jul 31;14:1218680. doi: 10.3389/fneur.2023.1218680. eCollection 2023.

本文引用的文献

1
Behçet's disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions.白塞病:一篇全面综述,重点关注流行病学、病因学、临床特征以及黏膜皮肤病变的管理。
J Dermatol. 2016 Jun;43(6):620-32. doi: 10.1111/1346-8138.13381. Epub 2016 Apr 14.
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The International Criteria for Behçet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria.国际白塞病诊断标准(ICBD):27 个国家对新标准敏感性和特异性的合作研究。
J Eur Acad Dermatol Venereol. 2014 Mar;28(3):338-47. doi: 10.1111/jdv.12107. Epub 2013 Feb 26.
3
IL-17A has an important role in the acute attacks of Behçet's disease.
白细胞介素-17A在白塞病急性发作中起重要作用。
J Invest Dermatol. 2010 Aug;130(8):2136-8. doi: 10.1038/jid.2010.114. Epub 2010 May 6.
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HLA-B51/B5 and the risk of Behçet's disease: a systematic review and meta-analysis of case-control genetic association studies.HLA - B51/B5与白塞病风险:病例对照基因关联研究的系统评价和荟萃分析
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Mucocutaneous lesions of Behcet's disease.白塞病的皮肤黏膜病变
Yonsei Med J. 2007 Aug 31;48(4):573-85. doi: 10.3349/ymj.2007.48.4.573.
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Clinical features and natural course of Behçet's disease in 661 cases: a multicentre study.661例白塞病的临床特征与自然病程:一项多中心研究
Br J Dermatol. 2007 Nov;157(5):901-6. doi: 10.1111/j.1365-2133.2007.08116.x. Epub 2007 Aug 17.
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Neuro-Behçet's disease in Caucasians: a study of 22 patients.高加索人群中的神经白塞病:22例患者的研究
Eur J Neurol. 2007 Feb;14(2):174-80. doi: 10.1111/j.1468-1331.2006.01613.x.
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Large thalamic mass due to neuro-Behcet disease.神经白塞病导致的丘脑巨大肿块。
Neurology. 2005 Aug 9;65(3):436. doi: 10.1212/01.wnl.0000179219.97769.6a.