Manne-Goehler Jennifer, Montana Livia, Gómez-Olivé Francesc Xavier, Rohr Julia, Harling Guy, Wagner Ryan G, Wade Alisha, Kabudula Chodziwadziwa W, Geldsetzer Pascal, Kahn Kathleen, Tollman Stephen, Berkman Lisa F, Bärnighausen Till W, Gaziano Thomas A
*Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA;†Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA;‡Harvard Center for Population and Development Studies, Harvard University, Cambridge, MA;§Medical Research Council/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa;‖Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa;¶Research Department of Infection and Population Health, University College London, London, United Kingdom;#INDEPTH Network, Accra, Ghana;**Institute of Public Health, University of Heidelberg, Heidelberg, Germany;††Department of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and‡‡Center for Health Decision Science, Harvard Medical School, Boston, MA.
J Acquir Immune Defic Syndr. 2017 Aug 15;75(5):561-567. doi: 10.1097/QAI.0000000000001445.
The prevalence of diabetes and hypertension has increased in HIV-positive populations, but there is limited understanding of the role that antiretroviral therapy (ART) programs play in the delivery of services for these conditions. The aim of this study is to assess the relationship between ART use and utilization of health care services for diabetes and hypertension.
Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa is a cohort of 5059 adults. The baseline study collects biomarker-based data on HIV, ART, diabetes, and hypertension and self-reported data on health care utilization. We calculated differences in care utilization for diabetes and hypertension by HIV and ART status and used multivariable logistic regressions to estimate the relationship between ART use and utilization of services for these conditions, controlling for age, sex, body mass index, education, and household wealth quintile.
Mean age, body mass index, hypertension, and diabetes prevalence were lower in the HIV-positive population (all P < 0.001). Multivariable logistic regression showed that ART use was significantly associated with greater odds of blood pressure measurement [adjusted odds ratio (aOR) 1.27, 95% confidence interval (CI): 1.04 to 1.55] and blood sugar measurement (aOR 1.26, 95% CI: 1.05 to 1.51), counseling regarding exercise (aOR 1.57, 95% CI: 1.11 to 2.22), awareness of hypertension diagnosis (aOR 1.52, 95% CI: 1.12 to 2.05), and treatment for hypertension (aOR 1.63, 95% CI: 1.21 to 2.19).
HIV-positive patients who use ART are more likely to have received health care services for diabetes and hypertension. This apparent ART advantage suggests that ART programs may be a vehicle for strengthening health systems for chronic care.
糖尿病和高血压在艾滋病毒阳性人群中的患病率有所上升,但对于抗逆转录病毒疗法(ART)项目在提供这些疾病服务方面所起的作用,人们了解有限。本研究的目的是评估ART的使用与糖尿病和高血压医疗服务利用之间的关系。
“非洲的健康与老龄化:南非一个深入社区的纵向研究”是一个包含5059名成年人的队列。基线研究收集基于生物标志物的艾滋病毒、ART、糖尿病和高血压数据以及关于医疗服务利用的自我报告数据。我们计算了艾滋病毒和ART状态不同的人群在糖尿病和高血压护理利用方面的差异,并使用多变量逻辑回归来估计ART的使用与这些疾病服务利用之间的关系,同时控制年龄、性别、体重指数、教育程度和家庭财富五分位数。
艾滋病毒阳性人群的平均年龄、体重指数、高血压和糖尿病患病率较低(所有P<0.001)。多变量逻辑回归显示,使用ART与血压测量几率更高(调整后的优势比[aOR]为1.27,95%置信区间[CI]:1.04至1.55)、血糖测量几率更高(aOR为1.26,95%CI:1.05至1.51)、运动咨询(aOR为1.57,95%CI:1.11至2.22)、高血压诊断知晓率(aOR为1.52,95%CI:1.12至2.05)以及高血压治疗几率更高(aOR为1.63,95%CI:1.21至2.19)显著相关。
使用ART的艾滋病毒阳性患者更有可能接受糖尿病和高血压的医疗服务。这种明显的ART优势表明,ART项目可能是加强慢性病护理卫生系统的一种手段。