Keller Damien, Beigelman-Aubry Catherine, Letovanec Igor, Bouchaab Hasna, Gonzalez Michel, Lovis Alban, Nicod Laurent P, Lazor Romain
Service de pneumologie, CHUV, 1011 Lausanne.
Service de radiodiagnostic et de radiologie interventionnelle, CHUV, 1011 Lausanne.
Rev Med Suisse. 2016 Nov 16;12(539):1976-1982.
Subsolid nodules represent almost 20% of all pulmonary nodules found incidentally at chest computed tomography (CT). Their detection is steadily rising, in parallel with the increasing number of CT scans performed. Subsolid nodules differ from solid lung nodules in several ways: morphology, course of progression, risk of malignancy and prognosis. Although they remain a diagnostic challenge, a good correlation has been established between radiological appearance and histopathology. Whilst 75% of persistent subsolid nodules represent a form of adenocarcinoma, their prognosis is generally excellent when resected. Non-resected subsolid nodules require a long follow-up of 3 to 5 years due to their slow-growing nature and high prevalence of malignancy. Specific guidelines have been published in 2013 and in 2015.
亚实性结节约占胸部计算机断层扫描(CT)偶然发现的所有肺结节的20%。随着CT扫描数量的增加,其检出率也在稳步上升。亚实性结节在几个方面与实性肺结节不同:形态、进展过程、恶性风险和预后。尽管它们仍然是一个诊断挑战,但放射学表现与组织病理学之间已建立了良好的相关性。虽然75%的持续性亚实性结节代表腺癌的一种形式,但切除后其预后通常很好。由于其生长缓慢且恶性患病率高,未切除的亚实性结节需要3至5年的长期随访。2013年和2015年已发布了具体指南。