Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
J Thorac Imaging. 2012 Jul;27(4):240-8. doi: 10.1097/RTI.0b013e31825d515b.
A new classification of lung adenocarcinoma has been proposed recently-the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. Abundant information from recent lung cancer computed tomography (CT) screening programs has increased our understanding of the strong, although imperfect, correlation between histologic findings of lung adenocarcinoma and subsolid pulmonary nodules on CT, including both "pure" ground-glass nodules (GGNs) and "part-solid" GGNs. Moreover, serial CT imaging has demonstrated stepwise progression of these nodules in a subset of patients, characterized by increase in size and density of GGNs and development of a solid component. Given the higher incidence of malignancy and the considerably lower growth rate of subsolid nodules, dedicated standardized guidelines for management of these nodules have been proposed, including long-term (≥3 y) CT follow-up using a low-dose technique. Radiologists should be familiar with the new terminology of lung adenocarcinomas and strategic management of subsolid pulmonary nodules.
最近提出了一种新的肺腺癌分类——国际肺癌研究协会/美国胸科学会/欧洲呼吸学会分类。来自最近肺癌计算机断层扫描（CT）筛查计划的大量信息增加了我们对肺腺癌的组织学发现与 CT 上的亚实性肺结节之间的强烈但不完美的相关性的理解，包括“纯”磨玻璃结节（GGN）和“部分实性” GGN。此外，系列 CT 成像显示在一部分患者中这些结节的逐步进展，其特征是 GGN 的大小和密度增加以及实性成分的发展。鉴于亚实性结节的恶性程度更高和生长速度明显较慢，已经提出了专门针对这些结节的管理标准指南，包括使用低剂量技术进行长期（≥3 年）CT 随访。放射科医生应该熟悉肺腺癌的新术语和亚实性肺结节的策略性管理。
