Robinson Deanne Mraz, Frulla Ashton P
J Drugs Dermatol. 2017 Jul 1;16(7):707-710.
INTRODUCTION: A topical proprietary procedural enhancement system (PES) containing a combination of active ingredients including a tripeptide and hexapeptide (TriHex Technology™, Alastin Procedure Enhancement Invasive System, ALASTIN Skincare™, Inc., Carlsbad, CA) has been used successfully to aid in healing and improve symptomatology following resurfacing procedures.
METHODS: PES (Gentle Cleanser, Regenerating Skin Nectar with TriHex Technology™, Ultra Nourishing Moisturizer with TriHex Technology™, Soothe + Protect Recovery Balm, Broad Spectrum 30+ Sunscreen) was compared to a basic regimen (Aquaphor™, Cerave™ cleanser, Vanicream™, Alastin Broad Spectrum 30+ Sunscreen) in a split face/ décolleté trial following fractional non-ablative thulium-doped resurfacing treatment to the face or décolleté. The skin was pre-conditioned and treated during and after the procedure using the two regimens.
RESULTS: A blinded investigator rated the PES statistically superior to the basic regimen on healing post-laser treatment on day 4 based on lentigines, texture, and Global Skin Quality. Subjects also reported 'better looking and feeling' skin on the PES side.
CONCLUSION: PES appears to improve healing post-non ablative thulium-doped resurfacing treatment to the face/décolleté in comparison with standard of care.
J Drugs Dermatol. 2017;16(7):707-710.
.一种局部专用的程序增强系统（PES），其含有包括三肽和六肽在内的活性成分组合（TriHex Technology™，Alastin程序增强侵入性系统，ALASTIN Skincare™公司，加利福尼亚州卡尔斯巴德）已成功用于辅助愈合并改善表面重修术后的症状。
在对面部或颈部进行非剥脱性掺铥激光表面重修治疗后的半脸/颈部试验中，将PES（温和洁面乳、含TriHex Technology™的再生肌肤精华素、含TriHex Technology™的超滋养保湿霜、舒缓+保护修复膏、广谱30+防晒霜）与基本疗法（Aquaphor™、Cerave™洁面乳、凡丽霜™、Alastin广谱30+防晒霜）进行比较。在手术期间及术后使用这两种疗法对皮肤进行预处理和治疗。
一位盲法研究者基于雀斑、质地和整体皮肤质量，在第4天评定PES在激光治疗后的愈合方面在统计学上优于基本疗法。受试者也报告PES一侧的皮肤“外观和感觉更好”。
与标准护理相比，PES似乎能改善面部/颈部非剥脱性掺铥激光表面重修治疗后的愈合情况。
《皮肤药物学杂志》2017年；16(7):707 - 710。
