Sun Yanming, Guo Wei, Li Guiying, He Shufang, Lu Hongyan
1 Beijing Center for Diseases Prevention and Control, Beijing, China.
2 Division of Epidemiology, 196543 National Center for AIDS/STD Control and Prevention , Chinese Center for Disease Control and Prevention, Beijing, China.
Int J STD AIDS. 2018 Jan;29(1):30-37. doi: 10.1177/0956462417715174. Epub 2017 Jul 11.
The objective of this study was to monitor the trend of addiction drug use and its relationship with sexually transmitted infections (STIs) among female drug users (FDUs). Serial cross-sectional surveys were conducted during 2010-2014 among FDUs in Beijing to collect information on addiction drug usage, sexual behaviors, and STI prevalence. Characteristics were analyzed and compared between traditional and synthetic drug users among FDUs by logistic regression method. A total of 3859 FDUs were surveyed during 2010-2014, with the median age being 32.7 years old. The proportion of synthetic drug users among FDUs increased from 43.7% in 2010 to 70.7% in 2014. Compared with traditional drug users, synthetic drug users were younger (P < 0.001), lacked education (P < 0.001), were unmarried (P < 0.001), and were non-local residents (P < 0.001). No significant difference was found with condom usage during sexual activity between traditional and synthetic drug FDUs. However, the engagement of commercial sexual activities (P < 0.001) and syphilis prevalence (P < 0.001) among synthetic drug users were significantly higher than traditional drug users. Synthetic drug abuse appears to be correlated with commercial sex behavior and higher syphilis prevalence among FDUs. Tailored strategies on health education to curb the prevalence of synthetic drug abuse are urgently needed in Beijing.
本研究的目的是监测女性吸毒者（FDU）中成瘾药物使用趋势及其与性传播感染（STI）的关系。2010年至2014年期间，对北京的女性吸毒者进行了系列横断面调查，以收集关于成瘾药物使用、性行为和性传播感染患病率的信息。采用逻辑回归方法分析和比较女性吸毒者中传统吸毒者和合成毒品使用者的特征。2010年至2014年期间共调查了3859名女性吸毒者，中位年龄为32.7岁。女性吸毒者中合成毒品使用者的比例从2010年的43.7%增至2014年的70.7%。与传统吸毒者相比，合成毒品使用者更年轻（P＜0.001）、受教育程度低（P＜0.001）、未婚（P＜0.001）且非本地居民（P＜0.001）。传统和合成毒品女性吸毒者在性行为期间使用避孕套方面未发现显著差异。然而，合成毒品使用者中商业性活动的参与度（P＜0.001）和梅毒患病率（P＜0.001）显著高于传统吸毒者。合成毒品滥用似乎与女性吸毒者中的商业性行为和较高的梅毒患病率相关。北京迫切需要制定针对性的健康教育策略以遏制合成毒品滥用的流行。
