[Factors related to syphilis and other infections among female drug users in Shandong women's compulsory drug rehabilitation center in 2015].

To analyze the prevalence of HIV, syphilis and related factors among female drug users in Shandong women's compulsory drug rehabilitation center(SWCDRC). During May 2015, we used a cluster sampling method for drug users in SWCDRC, with a questionnaire and serological testing. We included respondents who volunteered to take part in this study, had clear histories of drug abuse, and had no symptoms of psychosis or current drug use; 451 women participated. The questionnaire addressed socio-demographic information and the participants' health knowledge, including AIDS knowledge, behavioral information, drug use, and STD treatment. We also drew 5 ml blood from each subject for serological tests of HIV and syphilis. Chi-square test was used to compare syphilis antibody positive rate among drug users who had different characteristics. Multi-factor unconditioned logistic regression model was used to explore related factors about syphilis infection of women drug users. Subjects' mean age was(27.25±7.06)years. Of the 451 women, 33.5%(151/451)tested positive for syphilis and 2.2%(10/451)for HIV. The rate of syphilis antibody(SAb)positive whether providing commercial server, providing: 47.2%(25/53); no providing: 31.6%(125/396); χ=5.12, =0.024. The SAb rate from whether having temporary sexual behavior, having: 47.4%(91/192); no having: 23.6%(60/254); χ=27.6, <0.001. The SAb rate of subjects who tested positive for herpes simplex virus-2(HSV-2)was 39.4%(128/325); for those who tested negative it was 18.3%(23/126); χ=18.2, <0.001. The SAb rate by frequency of drug use was ≥3 times a week: 36.9%(106/287);<3 times per week: 27.3%(42/154); χ=4.20, =0.041. Compared with subjects who were unmarried, divorced, or widowed drug users, the (95% )for SAb among subjects who cohabited with a partner was 2.19(1.36- 3.51). Compared with subjects who had not been having temporary sexual behavior, the (95%)for SAb among subjects who had been having temporary sexual behavior was 2.59(1.65-4.05). Compared with HSV-2 subjects, the (95%)for SAb among subjects who were HSV-2 was 2.69(1.57-4.59). HIV and syphilis infection rate among female drug users in SWCDRC were significantly higher than in the general population. Subjects who had provided commercial server in the previous 12 months, had temporary sexual behavior in the previous 12 months, were HSV-2, used drugs ≥3 times per week or cohabitated with a partner had higher syphilis prevalence.