Saito Megumi, Ando-Tanabe Noriko, Arita Etsuko
Department of Medical Psychology, Pharmaceutical Education Center, Kitasato University School of Pharmacy, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
BMC Health Serv Res. 2017 Jul 11;17(1):475. doi: 10.1186/s12913-017-2431-9.
Better insight and knowledge on factors associated with perception of medication numbers and amounts would contribute greatly to our current understanding of patient psychological response regarding taking medications, and would allow us to improve drug administration support and adherence. This study explored associations between attitudes toward medication dosage in a questionnaire survey that examined demographic characteristics, the number of tablets and types of prescription medications considered excessive by participants, current medication and supplement use, personal experiences with medications, and perceptions surrounding medications.
An original anonymous questionnaire was used for this survey. A total of 934 university students completed and returned surveys with no missing data.
Mean values ± standard deviation for excessive thresholds for tablets and types of medications reported by all participants were 4.21 ± 1.63 tablets and 4.00 ± 1.25 medications, respectively. The number of tablets considered excessive was analyzed using a multiple regression model, which accounted for the variance (model-adjusted R = 0.095, p < 0.001) between statistically significant factors, including personal experience with a major illness, supplement use, aversion to taking medications, gender, university departmental affiliation, and experience with family members or acquaintances who took excessive amounts of medications (|beta| > 0.094, p < 0.01). The number of medications considered excessive was subject to a multiple regression analysis (model-adjusted R = 0.087 p < 0.01), which revealed statistically significant factors, including personal experience with a major illness, prescription medication use, aversion to taking medications, gender, university departmental affiliation, and experience with family members or acquaintances who took excessive amounts of medications (|beta| > 0.084, p < 0.01).
Individual attitudes toward medication dosage are influenced by individual factors. Thus, patients should be provided with personalized advice when they receive medication instructions.
深入了解与药物数量和剂量认知相关的因素，将极大地有助于我们目前对患者服药心理反应的理解，并使我们能够改进药物管理支持和依从性。本研究在一项问卷调查中探讨了对药物剂量的态度之间的关联，该调查考察了人口统计学特征、参与者认为过量的药片数量和处方药类型、当前药物和补充剂的使用情况、个人用药经历以及对药物的认知。
本调查使用了一份原始的匿名问卷。共有934名大学生完成并返回了无缺失数据的调查问卷。
所有参与者报告的药片和药物类型过量阈值的平均值±标准差分别为4.21±1.63片和4.00±1.25种药物。使用多元回归模型分析了被认为过量的药片数量，该模型解释了包括重大疾病个人经历、补充剂使用、厌恶服药、性别、大学所属院系以及家庭成员或熟人服用过量药物的经历等统计学显著因素之间的方差（模型调整R = 0.095，p < 0.001）（|β| > 0.094，p < 0.01）。对被认为过量的药物数量进行了多元回归分析（模型调整R = 0.087，p < 0.01），结果显示统计学显著因素包括重大疾病个人经历、处方药使用、厌恶服药、性别、大学所属院系以及家庭成员或熟人服用过量药物的经历（|β| > 0.084，p < 0.01）。
个体对药物剂量的态度受个体因素影响。因此，在为患者提供用药说明时，应给予个性化建议。
