Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Department of Infectious Diseases, Chonnam National University Medical School, Gwang-ju, Republic of Korea.
Clin Microbiol Infect. 2018 Mar;24(3):279-282. doi: 10.1016/j.cmi.2017.07.005. Epub 2017 Jul 8.
To investigate the concordance of results of blood and tissue cultures in patients with pyogenic spondylitis.
We searched for patients with pyogenic spondylitis in whom microorganisms were isolated from both blood and tissue cultures by retrospective review of medical records in three tertiary university-affiliated hospitals between January 2005 and December 2015. The species and antimicrobial susceptibility patterns of isolates from blood and tissue cultures were compared.
Among 141 patients with pyogenic spondylitis in whom microorganisms were isolated from both blood and tissue cultures, the species of blood and tissue isolates were identical in 135 patients (95.7%, 135/141). Excluding the four anaerobic isolates, we investigated antimicrobial susceptibility patterns of 131 isolates of the same species from blood and tissue cultures. Antibiotic susceptibility patterns were identical in 128 patients (97.7%, 128/131). The most common isolates were Staphylococcus aureus (86 patients; 85 concordant and one discordant), followed by streptococcus (24 patients; 22 concordant and two discordant), and Escherichia coli (eight patients; all concordant).
We suggest that a positive blood culture from patients with pyogenic spondylitis could preclude the need for additional tissue cultures, especially when S. aureus and streptococcus grew in blood cultures.
研究化脓性脊柱炎患者血液和组织培养结果的一致性。
我们通过回顾 2005 年 1 月至 2015 年 12 月期间三所三级大学附属医院的病历，对血液和组织培养中均分离出微生物的化脓性脊柱炎患者进行了回顾性研究。比较了血液和组织培养分离株的种类和抗菌药物敏感性模式。
在 141 例血液和组织培养中均分离出微生物的化脓性脊柱炎患者中，135 例（95.7%，135/141）患者的血液和组织分离株的种类相同。排除 4 株厌氧菌后，我们研究了来自血液和组织培养的相同种类的 131 株分离株的抗菌药物敏感性模式。128 例患者（97.7%，128/131）的抗生素敏感性模式相同。最常见的分离株是金黄色葡萄球菌（86 例；85 例一致，1 例不一致），其次是链球菌（24 例；22 例一致，2 例不一致）和大肠杆菌（8 例；均一致）。
我们建议，化脓性脊柱炎患者血液培养阳性可排除进一步进行组织培养的需要，尤其是当金黄色葡萄球菌和链球菌在血液培养中生长时。
