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巴西的安眠药使用情况:一项基于人群的横断面研究。

Sleeping pill use in Brazil: a population-based, cross-sectional study.

作者信息

Kodaira Katia, Silva Marcus Tolentino

机构信息

Universidade de Sorocaba, Post-Graduate Program in Pharmaceutical Sciences, Sorocaba, São Paulo, Brazil.

Faculty of Medicine, Federal University of Amazonas, Manaus, Brazil.

出版信息

BMJ Open. 2017 Jul 10;7(7):e016233. doi: 10.1136/bmjopen-2017-016233.

Abstract

OBJECTIVES

This study aimed to assess the prevalence of sleeping pill use in Brazil.

DESIGN

A population-based cross-sectional study with a three-stage cluster sampling design (census tracts, households and adult residents) was used.

SETTING

The Brazilian 2013 National Health Survey was used.

PARTICIPANTS

The study population consisted of household residents aged ≥18 years. A total of 60 202 individuals were interviewed, including 52.9% women, and 21% reported depressive symptoms.

OUTCOMES

The primary outcome was sleeping pill use, which was self-reported with the question, 'Over the past two weeks, have you used any sleeping pills?' The prevalence was calculated and stratified according to sociodemographic characteristics. The associated factors were identified from prevalence ratios (PRs) obtained through a Poisson regression with robust variance and adjusted for sex and age.

RESULTS

The prevalence of sleeping pill use was 7.6% (95% CI 7.3% to 8.0%), and the average treatment duration was 9.75 (95% CI 9.49 to 10.00) days. Self-medication was found in 11.2% (95% CI 9.6% to 12.9%) of users. The following factors were associated with sleeping pill use: female sex (PR=2.21; 95% CI 1.97 to 2.47), an age of ≥60 years (PR=5.43; 95% CI 4.14 to 7.11) and smoking (PR=1.47; 95% CI 1.28 to 1.68). Sleeping pill use was also positively associated with the severity of depressive symptoms (p<0.001), whereas alcohol intake was inversely associated (PR=0.66; 95% CI 0.56 to 0.77).

CONCLUSIONS

One in every 13 Brazilians adults uses sleeping pills. There is a lack of information about the reasons for this use. Actions are required to raise awareness about the risks. The results could assist programmes in targeting rational sleeping pill use and the identification of factors demanding intervention.

摘要

目的

本研究旨在评估巴西安眠药的使用 prevalence。

设计

采用基于人群的横断面研究,采用三阶段整群抽样设计(普查区、家庭和成年居民)。

背景

使用了巴西2013年全国健康调查。

参与者

研究人群包括年龄≥18岁的家庭居民。共访谈了60202人,其中女性占52.9%,21%报告有抑郁症状。

结果

主要结果是安眠药的使用,通过“在过去两周内,您是否使用过任何安眠药?”这一问题进行自我报告。根据社会人口学特征计算患病率并进行分层。通过具有稳健方差的泊松回归获得患病率比(PRs),并对性别和年龄进行调整,从而确定相关因素。

结果

安眠药的使用率为7.6%(95%可信区间7.3%至8.0%),平均治疗持续时间为9.75(95%可信区间9.49至10.00)天。11.2%(95%可信区间9.6%至12.9%)的使用者存在自我用药情况。以下因素与安眠药使用相关:女性(PR = 2.21;95%可信区间1.97至2.47)、年龄≥60岁(PR = 5.43;95%可信区间4.14至7.11)和吸烟(PR = 1.47;95%可信区间1.28至1.68)。安眠药的使用也与抑郁症状的严重程度呈正相关(p < 0.001),而酒精摄入量与之呈负相关(PR = 0.66;95%可信区间0.56至0.77)。

结论

每13名巴西成年人中就有1人使用安眠药。缺乏关于这种使用原因的信息。需要采取行动提高对风险的认识。这些结果可协助相关项目针对合理使用安眠药以及识别需要干预的因素。

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