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采用膳食摄入量监测和加权法对韩国人群的16种甜味剂进行安全性评估。

Safety assessment of 16 sweeteners for the Korean population using dietary intake monitoring and poundage method.

作者信息

Kim MeeKyung, Lee Gunyoung, Lim Ho Soo, Yun Sang Soon, Hwang Myungsil, Hong Jin-Hwan, Kwon Hoonjeong

机构信息

a Food Safety Evaluation Department , National Institute of Food and Drug Safety Evaluation , Cheongju-si , Republic of Korea.

b Department of Food and Nutrition , Seoul National University , Seoul , Republic of Korea.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Sep;34(9):1500-1509. doi: 10.1080/19440049.2017.1349344. Epub 2017 Jul 12.

DOI:10.1080/19440049.2017.1349344
PMID:28699833
Abstract

A sweetener is a food additive that imparts a sweet taste to food products. Sweeteners have been increasingly used in Korea since the approval of sodium saccharin and d-sorbitol in 1962. Unlike food contaminants, humans are exposed to food additives only through the consumption of processed food products. For exposure assessments of sweeteners, the dietary intakes of food products containing acesulfame-K, aspartame, saccharin-Na, and sucralose were determined, and the resulting calculated estimated daily intake (EDI) values were compared directly with each additive's ADI. The poundage method was used to calculate the daily intake per capita for 12 additional sweeteners, such as lactitol, for which appropriate analytical methods for food products do not exist. The risk, as evaluated by comparing the EDI with the ADI, was determined to be 2.9% for acesulfame-K, 0.8% for aspartame, 3.6% for saccharin-Na, 4.3% for steviol glycosides, and 2.1% for sucralose. No hazardous effect was predicted for the other 11 sweeteners, including lactitol.

摘要

甜味剂是一种给食品赋予甜味的食品添加剂。自1962年糖精钠和d -山梨醇获批以来,甜味剂在韩国的使用日益增加。与食品污染物不同,人类仅通过食用加工食品接触食品添加剂。为了对甜味剂进行暴露评估,测定了含有安赛蜜、阿斯巴甜、糖精钠和三氯蔗糖的食品的膳食摄入量,并将所得计算出的估计每日摄入量(EDI)值直接与每种添加剂的每日允许摄入量(ADI)进行比较。对于另外12种甜味剂,如乳糖醇(不存在适用于食品的合适分析方法),采用磅数法计算人均每日摄入量。通过将EDI与ADI进行比较评估得出,安赛蜜的风险为2.9%,阿斯巴甜为0.8%,糖精钠为3.6%,甜菊糖苷为4.3%,三氯蔗糖为2.1%。预计包括乳糖醇在内的其他11种甜味剂无有害影响。

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