没有证据表明凝血因子XIII - A基因座与HLA之间存在连锁关系。
No evidence for linkage between the loci for coagulation factor XIII-A and HLA.
作者信息
Nishigaki T, Tokunaga K, Ishii C, Omoto K, Akaza T, Akiyama N, Juji T, Murata S, Naito S, Saji H
出版信息
Hum Genet. 1986 Mar;72(3):266-7. doi: 10.1007/BF00291893.
PMID:2870019
Abstract
The linkage analysis between the locus for coagulation factor XIII-A (F13A) and HLA region genes (HLA-A, -C, -B) was performed. In males, the maximum of lod scores between F13A and HLA was 0.33 at 0 = 0.30, and in females lod scores were negative at all values of 0. The results provided no evidence for close linkage between F13A and HLA genes.
摘要
进行了凝血因子XIII - A（F13A）基因座与HLA区域基因（HLA - A、- C、- B）之间的连锁分析。在男性中，F13A与HLA之间的最大lod值在θ = 0.30时为0.33，而在女性中，所有θ值下的lod值均为阴性。结果没有提供F13A与HLA基因紧密连锁的证据。
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