线粒体苹果酸酶（ME2）基因座与凝血因子 XIIIA 亚基（F13A）基因座之间的连锁关系。
Linkage between the loci for mitochondrial malic enzyme (ME2) and coagulation factor XIIIA subunit (F13A).
作者信息
Kömpf J, Schunter F, Wernet P, Ritter H
出版信息
Hum Genet. 1985;70(1):43-4. doi: 10.1007/BF00389457.
PMID:2860058
Abstract
The locus for the mitochondrial malic enzyme (ME2) seems to be closely linked to the gene coding for the A subunit of coagulation factor XIII (F13A). From 18 informative families with 54 children a maximum lod score of 4.33 was obtained at a recombination fraction of 0.10. Since the assignment of F13A to the short arm of chromosome 6 was recently confirmed, the locus for ME2 can be added to this linkage group. The map order seems to be: GLO1 - HLA - F13A - ME2.
摘要
线粒体苹果酸酶（ME2）的基因座似乎与凝血因子 XIII（F13A）A 亚基的编码基因紧密连锁。在 18 个有信息的家庭及其 54 个孩子中，重组率为 0.10 时获得了最大 Lod 值 4.33。由于 F13A 定位于 6 号染色体短臂最近已得到证实，因此 ME2 的基因座可添加到该连锁群中。图谱顺序似乎是：GLO1 - HLA - F13A - ME2。
Zotero 插件