Eiberg H, Nielsen L S, Mohr J
Clin Genet. 1984 Nov;26(5):385-8. doi: 10.1111/j.1399-0004.1984.tb01077.x.
The polymorphism of the blood clotting factor F13A was examined in some of our Danish material of normal families. A total of four alleles were recognized, with allele frequencies as follows: F13A *1 = 0.817, F13A *2 = 0.177, F13A *4 = 0.003 and a new allele F13A *5 = 0.003. The distribution of unrelated individuals did not deviate significantly from the Hardy-Weinberg expectation. Linkage of F13A with HLA was confirmed (z = 5.18, theta = 0.17 in males and z = 0.14, theta = 0.37 in females). The sequence of the three systems F13A, HLA and GLO was found to be F13A-HLA-GLO as judged from two families each with a recombinant within the HLA system in males.
我们在一些丹麦正常家庭材料中检测了凝血因子F13A的多态性。共识别出四个等位基因，其等位基因频率如下：F13A *1 = 0.817，F13A *2 = 0.177，F13A *4 = 0.003以及一个新的等位基因F13A *5 = 0.003。无关个体的分布与哈迪-温伯格预期无显著偏差。证实了F13A与HLA的连锁关系（男性中z = 5.18，θ = 0.17；女性中z = 0.14，θ = 0.37）。从两个男性家庭中各有一个在HLA系统内发生重组的家庭判断，F13A、HLA和GLO这三个系统的顺序为F13A - HLA - GLO。
