Kogan S J, Gill B, Bennett B, Smey P, Reda E F, Levitt S B
J Urol. 1986 Apr;135(4):758-61. doi: 10.1016/s0022-5347(17)45842-3.
We reviewed the medical records of 65 boys with surgically and pathologically proved monorchism. A striking laterality to the left side was identified. In 83 per cent of the patients wolffian structures were present and in 20 per cent microscopic evidence of a terminal nubbin of hyalinized, calcified or hemosiderin-containing tissue was noted. These findings strongly suggest that in most instances of monorchism a testis had been present and had undergone subsequent in utero degeneration. Characterization of the hormonal changes associated with unilateral absent testes was done by determining fasting morning levels of luteinizing hormone and follicle-stimulating hormone. In a subgroup of monorchid boys and age-matched prepubertal unilateral cryptorchid boys luteinizing hormone release factor stimulation also was performed to determine if endocrine analysis could predict the absence of 1 testis.
我们查阅了65例经手术和病理证实为单睾症男孩的病历。发现明显偏向左侧。83%的患者存在中肾管结构，20%的患者有显微镜下可见的透明化、钙化或含铁血黄素组织终末小结节的证据。这些发现强烈提示，在大多数单睾症病例中，曾存在一个睾丸，且在子宫内经历了随后的退化。通过测定早晨空腹时的黄体生成素和卵泡刺激素水平，对与单侧睾丸缺如相关的激素变化进行了表征。在一组单睾症男孩和年龄匹配的青春期前单侧隐睾男孩亚组中，还进行了黄体生成素释放因子刺激试验，以确定内分泌分析是否能预测一侧睾丸缺如。
