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慢性肾脏病患者的糖尿病管理

Management of diabetes mellitus in patients with chronic kidney disease.

作者信息

Hahr Allison J, Molitch Mark E

机构信息

Division of Endocrinology, Metabolism, and Molecular Medicine, Northwestern University Feinberg School of Medicine, 645 N. Michigan Avenue, Suite 530, 60611 Chicago, Illinois USA.

出版信息

Clin Diabetes Endocrinol. 2015 Jun 4;1:2. doi: 10.1186/s40842-015-0001-9. eCollection 2015.

Abstract

Glycemic control is essential to delay or prevent the onset of diabetic kidney disease. There are a number of glucose-lowering medications available but only a fraction of them can be used safely in chronic kidney disease and many of them need an adjustment in dosing. The ideal target hemoglobin A1c is approximately 7 % but this target is adjusted based on the needs of the patient. Diabetes control should be optimized for each individual patient, with measures to reduce diabetes-related complications and minimize adverse events. Overall care of diabetes necessitates attention to multiple aspects, including reducing the risk of cardiovascular disease, and often, multidisciplinary care is needed.

摘要

血糖控制对于延缓或预防糖尿病肾病的发生至关重要。有多种降糖药物可供使用,但其中只有一小部分能在慢性肾病患者中安全使用,而且许多药物需要调整剂量。理想的糖化血红蛋白A1c目标约为7%,但该目标会根据患者的需求进行调整。应针对每位患者优化糖尿病控制,采取措施减少糖尿病相关并发症并将不良事件降至最低。糖尿病的整体护理需要关注多个方面,包括降低心血管疾病风险,而且通常需要多学科护理。

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