Damascus University, Damascus, Syria.
Université Catholique de Louvain, Brussels, Belgium.
Sleep Breath. 2018 May;22(2):277-286. doi: 10.1007/s11325-017-1538-x. Epub 2017 Jul 12.
Sleep-disordered breathing (SDB) is relatively common in general population as well as in patients with neuromuscular disease. SDB comprises a wide spectrum of disorders varying from simple snoring to complete closure of the upper airway as seen in obstructive sleep apnoea (OSA). It includes also other disorders like prolonged hypoxemia, hypoventilation, and central sleep apnoea (CSA). Neuromuscular diseases (NMD) form a group of disorders that can cause significant reduction in the quality and span of life. The involvement of respiratory system in the context of these disorders is the most serious complication, and it is considered as the leading cause of death in those patients. NMD can affect ventilation, cough, swallowing, and phonation. The involvement of respiratory muscles makes NMD patients vulnerable to sleep-disordered breathing with a significant prevalence of SDB among such patients.
睡眠呼吸障碍（SDB）在普通人群以及神经肌肉疾病患者中较为常见。SDB 包括一系列广泛的疾病，从单纯打鼾到上气道完全闭塞（如阻塞性睡眠呼吸暂停（OSA））。它还包括其他疾病，如长时间低氧血症、低通气和中枢性睡眠呼吸暂停（CSA）。神经肌肉疾病（NMD）是一组可导致生活质量和寿命显著下降的疾病。在这些疾病中，呼吸系统受累是最严重的并发症，被认为是这些患者死亡的主要原因。NMD 可影响通气、咳嗽、吞咽和发声。呼吸肌受累使 NMD 患者易患睡眠呼吸障碍，此类患者 SDB 的患病率较高。
