Department of Paediatrics, Midland Regional Hospital, Mullingar, Co, Westmeath.
Department of Paediatrics and Child Health, Cork University Hospital, Wilton, Cork, Ireland.
Diabet Med. 2017 Nov;34(11):1603-1607. doi: 10.1111/dme.13425. Epub 2017 Aug 3.
To establish the prevalence of paediatric Type 2 diabetes in the Republic of Ireland and describe patient demographics, initial presentation, management, outcomes, comorbidities and complications.
Using a standardized proforma we conducted a cross-sectional survey of children and adolescents aged < 16 years with a diagnosis of Type 2 diabetes between October and December 2015 in each of the 19 centres in the Republic of Ireland responsible for the care of children with diabetes.
Twelve cases of Type 2 diabetes were identified, giving a prevalence in children aged <16 years of 1.2/100 000 (95% CI 0.6 to 2). Six of these children (50%) were white, two (33%) of whom were members of the travelling community. Four (33%) were of black ethnicity. The prevalence of Type 2 diabetes in traveller children was 16.1/100 000 (95% CI 1.9 to 58.1) and was similar to that in black children, a known high-risk group, which was 13.3/100 000 (95% CI 3.6 to 34.1). The median current HbA value was 51 mmol/mol (6.8%) and four (33%) of the children achieved the International Society for Pediatric and Adolescent Diabetes target HbA of ≤48 mmol/mol (6.5%). Seven (59%) children were managed on metformin monotherapy, three (25%) were managed on insulin and metformin in combination, and two (16%) were receiving dietary management.
This was the first national study to estimate the prevalence of childhood Type 2 diabetes in Ireland. Despite their white ethnicity, traveller children appear to be a high-risk group, but this finding requires further study.
在爱尔兰共和国确定儿童 2 型糖尿病的流行情况,并描述患者人口统计学特征、初始表现、治疗、结局、合并症和并发症。
我们使用标准化表格,对 2015 年 10 月至 12 月期间在爱尔兰共和国负责儿童糖尿病护理的 19 个中心诊断为 2 型糖尿病的年龄<16 岁的儿童和青少年进行了横断面调查。
确定了 12 例 2 型糖尿病病例,<16 岁儿童的患病率为 1.2/100000(95%CI 0.6 至 2)。其中 6 例(50%)为白人,2 例(33%)为流动社区成员。4 例(33%)为黑人。流动儿童 2 型糖尿病的患病率为 16.1/100000(95%CI 1.9 至 58.1),与已知的高危人群黑人儿童的患病率相似,为 13.3/100000(95%CI 3.6 至 34.1)。目前的中位 HbA 值为 51 mmol/mol(6.8%),4 例(33%)儿童达到国际儿童青少年糖尿病协会的目标 HbA 值≤48 mmol/mol(6.5%)。7 例(59%)儿童接受二甲双胍单药治疗,3 例(25%)儿童接受胰岛素和二甲双胍联合治疗,2 例(16%)儿童接受饮食管理。
这是首次在爱尔兰全国范围内估计儿童 2 型糖尿病的患病率。尽管他们的种族是白人,但流动儿童似乎是一个高危人群,但这一发现需要进一步研究。