Sadowska Joanna, Bruszkowska Magda
Department of Human Nutrition Physiology, West Pomeranian University of Technology in Szczecin, Poland.
Acta Sci Pol Technol Aliment. 2017 Apr-Jun;16(2):231-240. doi: 10.17306/J.AFS.0482.
The objective of this study was to compare, in an animal model, the effect of different sugar types (sucrose vs. high-fructose corn syrup 55%) consumed as 10% by weight of the diet (11.6% of daily caloric intake) on the amount of food consumed, body weight, fatty tissue deposits, concentrations of selected lipids, and atherogenic indices of blood plasma. Material and method. The experiment was carried out on 30 5-month-old Wistar male rats, fed three differ- ent diets, containing, amongst other foods, (1) ground unrefined cereal grains, (2) sucrose, (3) high-fructose corn syrup. Results. Weight gains in animals on sucrose or high-fructose corn syrup diets were higher than those con- suming basic feed, but the effect was not associated with perivisceral fat accumulation. It has been found that all the atherogenic indices (Castelli’s Risk Index I, Castelli’s Risk Index II, Atherogenic Index of Plasma, Atherogenic Coefficient) were statistically significantly higher in animals on a high-fructose corn syrup diet compared to both the control group and those on a sucrose diet. Conclusion. The effect of the 55% high-fructose corn syrup on the tested parameters of lipid metabolism was not equivalent to that of sucrose. Using HFCS-55 instead of sucrose has an adverse effect on blood lipid parameters, while weight gains and peri-organ fat deposits are comparable. Moreover, the obtained results confirm that tested animals were susceptible to the adverse effects of sugars added to their diet, even in small amounts. This emphasises the need to precisely control the amount of added sugars in.
nd. The objective of this study was to compare, in an animal model, the effect of different sugar types (sucrose vs. high-fructose corn syrup 55%) consumed as 10% by weight of the diet (11.6% of daily caloric intake) on the amount of food consumed, body weight, fatty tissue deposits, concentrations of selected lipids, and atherogenic indices of blood plasma. Material and method. The experiment was carried out on 30 5-month-old Wistar male rats, fed three differ- ent diets, containing, amongst other foods, (1) ground unrefined cereal grains, (2) sucrose, (3) high-fructose corn syrup.
Weight gains in animals on sucrose or high-fructose corn syrup diets were higher than those con- suming basic feed, but the effect was not associated with perivisceral fat accumulation. It has been found that all the atherogenic indices (Castelli’s Risk Index I, Castelli’s Risk Index II, Atherogenic Index of Plasma, Atherogenic Coefficient) were statistically significantly higher in animals on a high-fructose corn syrup diet compared to both the control group and those on a sucrose diet.
The effect of the 55% high-fructose corn syrup on the tested parameters of lipid metabolism was not equivalent to that of sucrose. Using HFCS-55 instead of sucrose has an adverse effect on blood lipid parameters, while weight gains and peri-organ fat deposits are comparable. Moreover, the obtained results confirm that tested animals were susceptible to the adverse effects of sugars added to their diet, even in small amounts. This emphasises the need to precisely control the amount of added sugars in the diet.
本研究的目的是在动物模型中比较，当饮食中按重量计10%（占每日热量摄入的11.6%）摄入不同类型的糖（蔗糖与55%的高果糖玉米糖浆）时，对食物摄入量、体重、脂肪组织沉积、特定脂质浓度以及血浆动脉粥样硬化指数的影响。材料与方法。实验在30只5个月大的雄性Wistar大鼠身上进行，给它们喂食三种不同的饮食，除其他食物外，分别含有（1）磨碎的未精制谷物，（2）蔗糖，（3）高果糖玉米糖浆。结果。食用蔗糖或高果糖玉米糖浆饮食的动物体重增加高于食用基础饲料的动物，但这种影响与内脏周围脂肪堆积无关。研究发现，与对照组和食用蔗糖饮食的动物相比，食用高果糖玉米糖浆饮食的动物所有动脉粥样硬化指数（卡斯泰利风险指数I、卡斯泰利风险指数II、血浆动脉粥样硬化指数、动脉粥样硬化系数）在统计学上均显著更高。结论。55%的高果糖玉米糖浆对脂质代谢测试参数的影响与蔗糖不同。用55%的高果糖玉米糖浆替代蔗糖对血脂参数有不利影响，而体重增加和器官周围脂肪沉积相当。此外，所得结果证实，受试动物即使摄入少量添加到饮食中的糖也易受其不利影响。这强调了精确控制饮食中添加糖量的必要性。
本研究的目的是在动物模型中比较，当饮食中按重量计10%（占每日热量摄入的11.6%）摄入不同类型的糖（蔗糖与55%的高果糖玉米糖浆）时，对食物摄入量、体重、脂肪组织沉积、特定脂质浓度以及血浆动脉粥样硬化指数的影响。材料与方法。实验在30只5个月大的雄性Wistar大鼠身上进行，给它们喂食三种不同的饮食，除其他食物外，分别含有（1）磨碎的未精制谷物，（2）蔗糖，（3）高果糖玉米糖浆。
食用蔗糖或高果糖玉米糖浆饮食的动物体重增加高于食用基础饲料的动物，但这种影响与内脏周围脂肪堆积无关。研究发现，与对照组和食用蔗糖饮食的动物相比，食用高果糖玉米糖浆饮食的动物所有动脉粥样硬化指数（卡斯泰利风险指数I、卡斯泰利风险指数II、血浆动脉粥样硬化指数、动脉粥样硬化系数）在统计学上均显著更高。
55%的高果糖玉米糖浆对脂质代谢测试参数的影响与蔗糖不同。用55%的高果糖玉米糖浆替代蔗糖对血脂参数有不利影响，而体重增加和器官周围脂肪沉积相当。此外，所得结果证实，受试动物即使摄入少量添加到饮食中的糖也易受其不利影响。这强调了精确控制饮食中添加糖量的必要性。
