Litovitz T
Pediatr Clin North Am. 1986 Apr;33(2):311-23. doi: 10.1016/s0031-3955(16)35004-0.
More than 6 per cent of poisonings involve alcohols and glycols, reflecting their availability in a wide range of household products, including aftershave, brake fluid, gas line antifreeze, model airplane fuel, mouthwash, rubbing alcohol, and windshield washing solution. Diagnosis involves recognition of an osmolal gap and variable degrees and delays in development of an anion gap metabolic acidosis. Therapeutic modalities are similar for methanol and ethylene glycol, both cases requiring ethanol-blocking of alcohol dehydrogenase and hemodialysis. More often, treatment of ethanol and isopropanol poisoning is limited to supportive care.
超过6%的中毒事件涉及酒精和二醇类物质,这反映出它们在多种家用产品中都可获取,包括须后水、制动液、输气管道防冻液、模型飞机燃料、漱口水、外用酒精和挡风玻璃清洗液。诊断包括识别渗透压间隙以及阴离子间隙代谢性酸中毒发展的不同程度和延迟情况。甲醇和乙二醇的治疗方式相似,两种情况都需要用乙醇阻断乙醇脱氢酶并进行血液透析。更常见的是,乙醇和异丙醇中毒的治疗仅限于支持性护理。