• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

噢哢类化合物作为高端进化产物的出现、生物合成及性质

Occurrences, biosynthesis and properties of aurones as high-end evolutionary products.

作者信息

Boucherle Benjamin, Peuchmaur Marine, Boumendjel Ahcène, Haudecoeur Romain

机构信息

Univ. Grenoble-Alpes, CNRS, DPM UMR 5063, CS 40700, 38058, Grenoble, France.

Univ. Grenoble-Alpes, CNRS, DPM UMR 5063, CS 40700, 38058, Grenoble, France.

出版信息

Phytochemistry. 2017 Oct;142:92-111. doi: 10.1016/j.phytochem.2017.06.017.

DOI:10.1016/j.phytochem.2017.06.017
PMID:28704688
Abstract

Recent years have witnessed a considerable renewed interest for the uncommon flavonoid class of aurones. The characterization of two major biosynthetic machineries involved in their biosynthesis in flowers has encouraged the revival of phytochemical studies and identification of original structures, a process started almost seventy-five years ago. This review draws up an exhaustive map of natural occurrences of aurones their biosynthetic pathways and roles, with the aim to link their original structural properties among flavonoids to their place in evolution and the selective advantages they bring to some of the most advanced taxa in the plant kingdom.

摘要

近年来,人们对不常见的黄酮类化合物奥洛酮类重新产生了浓厚的兴趣。参与其在花中生物合成的两种主要生物合成机制的表征,推动了植物化学研究的复兴以及原始结构的鉴定,这一过程始于近75年前。本综述绘制了奥洛酮类天然存在情况、其生物合成途径及作用的详尽图谱,旨在将它们在黄酮类化合物中的原始结构特性与其在进化中的地位以及它们给植物界一些最先进的类群带来的选择优势联系起来。

相似文献

1
Occurrences, biosynthesis and properties of aurones as high-end evolutionary products.噢哢类化合物作为高端进化产物的出现、生物合成及性质
Phytochemistry. 2017 Oct;142:92-111. doi: 10.1016/j.phytochem.2017.06.017.
2
Yellow flowers generated by expression of the aurone biosynthetic pathway.通过金合欢醇生物合成途径的表达产生的黄色花朵。
Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11075-80. doi: 10.1073/pnas.0604246103. Epub 2006 Jul 10.
3
Identification of cytotoxic and anti-inflammatory constituents from the bark of Toxicodendron vernicifluum (Stokes) F.A. Barkley.从漆树(Stokes)F.A. Barkley 的树皮中鉴定细胞毒性和抗炎成分。
J Ethnopharmacol. 2015 Mar 13;162:231-7. doi: 10.1016/j.jep.2014.12.071. Epub 2015 Jan 9.
4
New flavonoids with cytotoxicity from the roots of Flemingia latifolia.阔苞千斤拔根中具有细胞毒性的新黄酮类化合物。
Fitoterapia. 2015 Jul;104:97-101. doi: 10.1016/j.fitote.2015.05.015. Epub 2015 May 27.
5
Generation of Yellow Flowers of the Japanese Morning Glory by Engineering Its Flavonoid Biosynthetic Pathway toward Aurones.通过工程化日本牵牛花色氨酸生物合成途径生成黄色花朵的类黄酮。
Plant Cell Physiol. 2019 Aug 1;60(8):1871-1879. doi: 10.1093/pcp/pcz101.
6
Biochemistry and regulation of aurone biosynthesis.橙酮生物合成的生物化学与调控
Biosci Biotechnol Biochem. 2022 Apr 21;86(5):557-573. doi: 10.1093/bbb/zbac034.
7
Recent advances in the medicinal chemistry of aurones.奥罗宁类化合物的药物化学研究进展。
Curr Med Chem. 2012;19(18):2861-75. doi: 10.2174/092986712800672085.
8
Homology modeling and dynamics study of aureusidin synthase--an important enzyme in aurone biosynthesis of snapdragon flower.金雀花黄素合酶的同源建模与动力学研究——金鱼草花中橙酮生物合成的重要酶。
Int J Biol Macromol. 2011 Aug 1;49(2):134-42. doi: 10.1016/j.ijbiomac.2011.03.017. Epub 2011 Apr 4.
9
Aurones: interesting natural and synthetic compounds with emerging biological potential.噢哢类化合物:具有新出现生物学潜力的有趣天然及合成化合物。
Nat Prod Commun. 2012 Mar;7(3):389-94.
10
New aurone epoxide and auronolignan from the heartwood of Scop.从Scop.的心材中提取的新金合欢环氧物和金合欢木脂素
Nat Prod Res. 2019 Oct;33(19):2837-2844. doi: 10.1080/14786419.2018.1508141. Epub 2018 Dec 4.

引用本文的文献

1
Design and synthesis of novel indolinone Aurora B kinase inhibitors based on fragment-based drug discovery (FBDD).基于片段药物发现(FBDD)的新型吲哚啉酮Aurora B激酶抑制剂的设计与合成。
Mol Divers. 2025 Sep 10. doi: 10.1007/s11030-025-11353-w.
2
Exploring the anticancer potential of extracts and compounds from the heartwood of Cotinus coggygria Scop. wild growing in Serbia.探索塞尔维亚野生生长的黄栌心材提取物和化合物的抗癌潜力。
BMC Complement Med Ther. 2025 Feb 4;25(1):36. doi: 10.1186/s12906-025-04768-3.
3
Scaffold-Hopping Strategies in Aurone Optimization: A Comprehensive Review of Synthetic Procedures and Biological Activities of Nitrogen and Sulfur Analogues.
桥连跳跃策略在橙酮优化中的应用:氮和硫类似物的合成方法和生物活性的综合综述。
Molecules. 2024 Jun 13;29(12):2813. doi: 10.3390/molecules29122813.
4
Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities.具有抗菌活性的新型氨基和乙酰氨基奥酮的设计与合成
Antibiotics (Basel). 2024 Mar 26;13(4):300. doi: 10.3390/antibiotics13040300.
5
A concise update on the synthetic transformation of aurones asymmetric cycloaddition, annulation, and Michael/Mannich reactions.金酮的合成转化——不对称环加成、环化以及迈克尔/曼尼希反应的简要综述。
RSC Adv. 2024 Feb 20;14(9):6339-6359. doi: 10.1039/d3ra08575a. eCollection 2024 Feb 14.
6
Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones.奥酮类天然及合成类似物在抗糖尿病方面的最新研究趋势
Curr Issues Mol Biol. 2023 Oct 19;45(10):8461-8475. doi: 10.3390/cimb45100533.
7
Prenylated Flavonoids with Selective Toxicity against Human Cancers.具有选择性细胞毒性的类异戊二烯化黄酮类化合物。
Int J Mol Sci. 2023 Apr 18;24(8):7408. doi: 10.3390/ijms24087408.
8
Semisynthetic aurones A14 protects against T-cell acute lymphoblastic leukemia via suppressing proliferation and inducing cell cycle arrest with apoptosis.半合成金橙酮A14通过抑制增殖、诱导细胞周期停滞并伴随凋亡来预防T细胞急性淋巴细胞白血病。
Chin Med. 2022 Dec 12;17(1):137. doi: 10.1186/s13020-022-00693-6.
9
Evolution and function of red pigmentation in land plants.陆生植物中红色素的进化与功能。
Ann Bot. 2022 Nov 17;130(5):613-636. doi: 10.1093/aob/mcac109.
10
Snailase: A Promising Tool for the Enzymatic Hydrolysis of Flavonoid Glycosides From Plant Extracts.蜗牛酶:从植物提取物中酶解黄酮苷的一种有前景的工具。
Front Plant Sci. 2022 Jun 9;13:889184. doi: 10.3389/fpls.2022.889184. eCollection 2022.