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痴呆症患者抗精神病药物治疗与国家指令相关的趋势——瑞典背景综述

Trends in treatment with antipsychotic medication in relation to national directives, in people with dementia - a review of the Swedish context.

作者信息

Karlsson Staffan, Rahm Hallberg Ingalill, Midlöv Patrik, Fagerström Cecilia

机构信息

Department of Health Sciences, Lund University, -221 00, Lund, SE, Sweden.

School of Health and Welfare, Halmstad University, -301 18, Halmstad, SE, Sweden.

出版信息

BMC Psychiatry. 2017 Jul 14;17(1):251. doi: 10.1186/s12888-017-1409-9.

Abstract

BACKGROUND

The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care in nursing homes as reported in the most recent empirical studies on the topic, and to relate these trends to directives from the national authorities.

METHODS

The study included two scoping review studies based on searches of electronic databases as well as the Swedish directives in the field.

RESULTS

During the past decade, directives have been developed for antipsychotic medication in Sweden. These directives were generic at first, but have become increasingly specific and restrictive with time. The scoping review showed that treatment with antipsychotic drugs varied between 6% and 38%, and was higher in younger older persons and in those with moderate cognitive impairment and living in nursing homes for people with dementia. A decreasing trend in antipsychotic use has been seen over the last 15 years.

CONCLUSIONS

Directives from the authorities in Sweden may have had an impact on treatment with antipsychotic medication for people with dementia. Treatment with antipsychotic medication has decreased, while treatment with combinations of psychotropic medications is common. National directives may possibly be even more effective, if applied in combination with systematic follow-ups.

摘要

背景

本研究旨在探讨瑞典养老院痴呆护理中抗精神病药物治疗的趋势,这些趋势来自该主题的最新实证研究报告,并将这些趋势与国家当局的指令相关联。

方法

该研究包括两项基于电子数据库检索以及该领域瑞典指令的范围综述研究。

结果

在过去十年中,瑞典已制定了抗精神病药物的指令。这些指令最初是一般性的,但随着时间的推移变得越来越具体和严格。范围综述显示,抗精神病药物的治疗率在6%至38%之间变化,在年龄较小的老年人、中度认知障碍者以及居住在痴呆症患者养老院的人群中更高。在过去15年中,抗精神病药物的使用呈下降趋势。

结论

瑞典当局的指令可能对痴呆症患者的抗精神病药物治疗产生了影响。抗精神病药物治疗有所减少,而精神药物联合治疗很常见。如果与系统随访相结合,国家指令可能会更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bff/5513361/f316374f9a8f/12888_2017_1409_Fig1_HTML.jpg

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