Koerbin G, Potter J M, Andriolo K, West N P, Glasgow N, Hawkins C, Cavanaugh J A, Hickman P E
NSW Health Pathology, NSW, Australia; University of Canberra, ACT, Australia.
Australian National University Medical School, ACT, Australia; ACT Pathology, ACT, Australia.
Pathology. 2017 Aug;49(5):518-525. doi: 10.1016/j.pathol.2017.04.003. Epub 2017 Jul 10.
Reference limits or intervals are important benchmarks or tools that help the clinician to distinguish between a result that is most likely to lie within a 'healthy' or diseased category. It has been suggested that a review of haematology reference intervals is long overdue. In this study we report on our findings for analytes routinely measured in a complete blood count (CBC) performed on the Beckman Coulter LH 750 analyser and an additional comparative study using the Beckman Coulter LH 750, the Sysmex XN and Abbott Sapphire. The results from the comparative study indicate that bias would not prevent harmonisation of reference intervals for these common haematology parameters. The results offered by the Aussie Normals study represent good candidates as the basis for harmonisation reference intervals.
参考限值或区间是重要的基准或工具，可帮助临床医生区分最有可能处于“健康”或疾病类别的结果。有人认为，早就应该对血液学参考区间进行审查了。在本研究中，我们报告了在贝克曼库尔特LH 750分析仪上进行的全血细胞计数（CBC）中常规检测的分析物的研究结果，以及一项使用贝克曼库尔特LH 750、Sysmex XN和雅培蓝宝石进行的额外比较研究。比较研究的结果表明，偏差不会妨碍这些常见血液学参数参考区间的统一。澳大利亚正常研究提供的结果是作为统一参考区间基础的良好候选者。
