Gultekin Murat, Kucukyildiz Irem, Karaca Mujdegul Zayifoglu, Dundar Selin, Boztas Guledal, Turan Semra Hatice, Hacikamiloglu Ezgi, Keskinkilic Bekir
*Faculty of Medicine, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Hacettepe University; and †Department of Cancer Control, Public Health Institute, Turkish Ministry of Health, Ankara, Turkey.
Int J Gynecol Cancer. 2017 Sep;27(7):1525-1533. doi: 10.1097/IGC.0000000000001026.
The aim of this study was to evaluate nationwide gynecological cancer trends in Turkey.
National cancer registry data (2009-2013) of Turkish Ministry of Health were evaluated. Ovarian, cervical, endometrial, vulvar, vaginal, and tubal cancers are evaluated with respect to age of diagnosis, incidence rates within years, stage, histological distributions, and mortality rates. Data were collected from active cancer registry centers, which increased from 23% in 2009 to 47.5% coverage of the whole population by 2012, and mortality data (2010-2015) were obtained from the Turkish Statistical Institute.
A total of 16,023 gynecological cancers were evaluated among 116,940 female patients with cancer (13.7%). Average incidence for gynecological cancers was 22.7 of 100,000, representing 8437 total new cases annually. Incidence changes within time were not statistically significant, when evaluated for each tumor type. Estimated risk of gynecological cancer development before the age of 80 years was 3.08% (95% confidence interval, 3.07-3.09). The most common gynecological cancers were uterine corpus cancers, which were followed by ovarian and cervical carcinomas. Ovarian and uterine cancer incidences were closer to European levels rather than Asian countries, whereas cervical cancer incidence was extremely low. Gynecological cancers constituted an important fraction of cancer-related mortality in women by comprising approximately 10.35% of cancer-related deaths. Mortality rates due to gynecological cancers did not show a statistically significant increase within years.
This is the first national cancer registry report to be published for gynecological cancers by the Turkish Governmental Department. As a result, Turkish gynecological cancer epidemiological data were consistent with the data obtained from European and developed countries rather than Asian countries, except for cervical cancer incidence, which is extremely low.
本研究旨在评估土耳其全国范围内妇科癌症的发病趋势。
对土耳其卫生部的国家癌症登记数据（2009 - 2013年）进行评估。从诊断年龄、各年份发病率、分期、组织学分布及死亡率等方面对卵巢癌、宫颈癌、子宫内膜癌、外阴癌、阴道癌和输卵管癌进行评估。数据收集自活跃的癌症登记中心，其覆盖人口比例从2009年的23%增至2012年的47.5%，死亡率数据（2010 - 2015年）来自土耳其统计局。
在116,940名女性癌症患者中，共评估了16,023例妇科癌症（占13.7%）。妇科癌症的平均发病率为每10万人中22.7例，每年新增病例总数为8437例。对每种肿瘤类型进行评估时，发病率随时间的变化无统计学意义。80岁前患妇科癌症的估计风险为3.08%（95%置信区间，3.07 - 3.09）。最常见的妇科癌症是子宫体癌，其次是卵巢癌和宫颈癌。卵巢癌和子宫癌的发病率更接近欧洲水平而非亚洲国家，而宫颈癌发病率极低。妇科癌症约占女性癌症相关死亡的10.35%，在女性癌症相关死亡率中占重要比例。妇科癌症死亡率在各年份未显示出统计学上的显著增加。
这是土耳其政府部门发表的首份关于妇科癌症的国家癌症登记报告。结果显示，除宫颈癌发病率极低外，土耳其妇科癌症流行病学数据与从欧洲及发达国家获得的数据一致，而非与亚洲国家的数据一致。
