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印度注意缺陷多动障碍研究:叙事性综述。

ADHD research in India: A narrative review.

机构信息

Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry 605006, India.

Room No. 4091, Department of Psychiatry, 4th Floor Academic Block, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029, India.

出版信息

Asian J Psychiatr. 2017 Dec;30:11-25. doi: 10.1016/j.ajp.2017.07.022. Epub 2017 Jul 5.

Abstract

INTRODUCTION

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with no clear etiopathogenesis. Owing to unique socio cultural milieu of India, it is worthwhile reviewing research on ADHD from India and comparing findings with global research. Thereby, we attempted to provide a comprehensive overview of research on ADHD from India.

METHODS

A boolean search of articles published in English from September 1966 to January 2017 on electronic search engines Google Scholar, PubMed, IndMED, MedIND, using the search terms "ADHD", "Attention Deficit and Hyperactivity Disorder", "Hyperactivity" ,"Child psychiatry", "Hyperkinetic disorder", "Attention Deficit Disorder", "India"was carried out and peer - reviewed studies conducted among human subjects in India were included for review. Case reports, animal studies, previous reviews were excluded from the current review.

RESULTS

Results of 73 studies found eligible for the review were organized into broad themes such as epidemiology, etiology, course and follow up, clinical profile and comorbidity, assessment /biomarkers, intervention/treatment parameters, pathways to care and knowledge and attitude towards ADHD.

DISCUSSION

There was a gap noted in research from India in the domains of biomarkers, course and follow up and non-pharmacological intervention. The prevalence of ADHD as well as comorbidity of Bipolar Disorder was comparatively lower compared to western studies. The studies found unique to India include comparing the effect of allopathic intervention with Ayurvedic intervention, yoga as a non pharmacological intervention. There is a need for studies from India on biomarkers, studies with prospective research design, larger sample size and with matched controls.

摘要

简介

注意缺陷多动障碍(ADHD)是一种神经发育障碍,其病因学尚不清楚。由于印度独特的社会文化环境,有必要对印度的 ADHD 研究进行综述,并与全球研究结果进行比较。因此,我们试图提供印度 ADHD 研究的全面概述。

方法

使用电子搜索引擎 Google Scholar、PubMed、IndMED 和 MedIND,对 1966 年 9 月至 2017 年 1 月发表的英文文章进行布尔搜索,使用的搜索词是“ADHD”、“注意力缺陷多动障碍”、“多动”、“儿童精神病学”、“多动障碍”、“注意力缺陷障碍”、“印度”,纳入在印度进行的以人为研究对象的同行评议研究。排除病例报告、动物研究和综述。

结果

共检索到 73 项符合条件的研究,将其分为以下几大主题:流行病学、病因学、病程和随访、临床特征和共病、评估/生物标志物、干预/治疗参数、治疗途径、以及对 ADHD 的认识和态度。

讨论

印度在生物标志物、病程和随访以及非药物干预领域的研究存在空白。与西方研究相比,印度 ADHD 的患病率以及双相情感障碍的共病率较低。印度特有的研究包括比较同种医学干预与阿育吠陀干预的效果、瑜伽作为非药物干预。印度需要开展生物标志物研究,前瞻性研究设计的研究,以及更大样本量和匹配对照的研究。

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