Institute of Neuroscience/Newcastle University Institute for Ageing, Clinical Ageing Research Unit, Newcastle University, Newcastle upon Tyne, NE4 5PL, UK.
Newcastle upon Tyne Hospitals NHS foundation trust, Newcastle upon Tyne, UK.
Med Biol Eng Comput. 2018 Feb;56(2):289-296. doi: 10.1007/s11517-017-1669-z. Epub 2017 Jul 15.
Mobile eye-trackers are currently used during real-world tasks (e.g. gait) to monitor visual and cognitive processes, particularly in ageing and Parkinson's disease (PD). However, contextual analysis involving fixation locations during such tasks is rarely performed due to its complexity. This study adapted a validated algorithm and developed a classification method to semi-automate contextual analysis of mobile eye-tracking data. We further assessed inter-rater reliability of the proposed classification method. A mobile eye-tracker recorded eye-movements during walking in five healthy older adult controls (HC) and five people with PD. Fixations were identified using a previously validated algorithm, which was adapted to provide still images of fixation locations (n = 116). The fixation location was manually identified by two raters (DH, JN), who classified the locations. Cohen's kappa correlation coefficients determined the inter-rater reliability. The algorithm successfully provided still images for each fixation, allowing manual contextual analysis to be performed. The inter-rater reliability for classifying the fixation location was high for both PD (kappa = 0.80, 95% agreement) and HC groups (kappa = 0.80, 91% agreement), which indicated a reliable classification method. This study developed a reliable semi-automated contextual analysis method for gait studies in HC and PD. Future studies could adapt this methodology for various gait-related eye-tracking studies.
移动眼动追踪器目前用于真实世界任务(例如步态)中,以监测视觉和认知过程,特别是在衰老和帕金森病(PD)中。然而,由于其复杂性,很少对涉及此类任务中注视位置的上下文分析进行。本研究采用了经过验证的算法并开发了一种分类方法,以半自动地对移动眼动追踪数据进行上下文分析。我们进一步评估了所提出的分类方法的组内可靠性。移动眼动追踪器在五名健康老年对照组(HC)和五名 PD 患者的步行过程中记录了眼动。使用先前验证的算法识别注视,该算法经过调整可提供注视位置的静态图像(n=116)。注视位置由两名评分员(DH,JN)手动识别,并对位置进行分类。Cohen's kappa 相关系数确定了组内可靠性。该算法成功地为每个注视提供了静态图像,从而可以进行手动上下文分析。对于 PD(kappa=0.80,95%一致性)和 HC 组(kappa=0.80,91%一致性),对注视位置进行分类的组内可靠性很高,表明分类方法可靠。本研究开发了一种用于 HC 和 PD 步态研究的可靠半自动上下文分析方法。未来的研究可以将这种方法应用于各种与步态相关的眼动追踪研究中。