Braun J P, Bézille P, Rico A G
Reprod Nutr Dev (1980). 1986;26(1B):227-43.
Many different serum biochemical tests can help in the diagnosis of liver disturbances in ruminants. The best tests for hepato-cellular damage are the measurement of enzymes such as glutamate dehydrogenase, sorbitol dehydrogenase and, if available, arginase or ornithine carbamoyl transferase. Disturbances of biliary function can be investigated through the measurement of so-called "cholestasis enzyme markers" such as gammaglutamyl transferase or alkaline phosphatases; bilirubin and bile salts can also be helpful. Liver insufficiency can be approached through the measurement of serum albumin, fibrinogen and coagulation tests whereas inflammative and inductive processes are difficult to investigate. Moreover, liver clearances (bromosulfonephtalein or indocyanine green) can provide useful data about whole liver function.
许多不同的血清生化检测有助于诊断反刍动物的肝脏疾病。用于肝细胞损伤的最佳检测方法是测量谷氨酸脱氢酶、山梨醇脱氢酶等酶类，如果有条件，还可测量精氨酸酶或鸟氨酸氨甲酰基转移酶。胆汁功能紊乱可通过测量所谓的“胆汁淤积酶标志物”如γ-谷氨酰转移酶或碱性磷酸酶来研究；胆红素和胆汁盐也可能有帮助。肝功能不全可通过测量血清白蛋白、纤维蛋白原和凝血检测来评估，而炎症和诱导过程则难以研究。此外，肝脏清除率（溴磺酚酞或吲哚菁绿）可为全肝功能提供有用数据。
