Nazaran Amin, Carl Michael, Ma Yajun, Jerban Saeed, Zhu Yanchun, Lu Xing, Du Jiang, Chang Eric Y
Department of Radiology, University of California, San Diego, CA, United States.
Applied Science Lab, GE Healthcare, San Diego, CA, United States.
Magn Reson Imaging. 2017 Dec;44:60-64. doi: 10.1016/j.mri.2017.07.012. Epub 2017 Jul 15.
We present three-dimensional adiabatic inversion recovery prepared ultrashort echo time Cones (3D IR-UTE-Cones) imaging of cortical bone in the hip of healthy volunteers using a clinical 3T scanner.
A 3D IR-UTE-Cones sequence, based on a short pulse excitation followed by a 3D Cones trajectory, with a nominal TE of 32μs, was employed for high contrast morphological imaging of cortical bone in the hip of heathy volunteers. Signals from soft tissues such as muscle and marrow fat were suppressed via adiabatic inversion and signal nulling. T value of the cortical bone was also calculated based on 3D IR-UTE-Cones acquisitions with a series of TEs ranging from 0.032 to 0.8ms. A total of four healthy volunteers were recruited for this study. Average T values and the standard deviation for four regions of interests (ROIs) at the greater trochanter, the femoral neck, the femoral head and the lesser trochanter were calculated.
The 3D IR-UTE-Cones sequence provided efficient suppression of soft tissues with excellent image contrast for cortical bone visualization in all volunteer hips. Exponential single component decay was observed for all ROIs, with averaged T values ranging from 0.33 to 0.45ms, largely consistent with previously reported T values of cortical bone in the tibial midshaft.
The 3D IR-UTE-Cones sequence allows in vivo volumetric imaging and quantitative T measurement of cortical bone in the hip using a clinical 3T scanner.
我们使用临床3T扫描仪展示了健康志愿者髋部皮质骨的三维绝热反转恢复准备的超短回波时间锥体（3D IR-UTE-Cones）成像。
基于短脉冲激发随后是3D锥体轨迹的3D IR-UTE-Cones序列，标称回波时间（TE）为32μs，用于健康志愿者髋部皮质骨的高对比度形态学成像。通过绝热反转和信号归零抑制肌肉和骨髓脂肪等软组织的信号。还基于一系列TE范围从0.032到0.8ms的3D IR-UTE-Cones采集计算皮质骨的T值。本研究共招募了四名健康志愿者。计算了大转子、股骨颈、股骨头和小转子四个感兴趣区域（ROI）的平均T值和标准差。
3D IR-UTE-Cones序列有效地抑制了软组织，在所有志愿者髋部中为皮质骨可视化提供了出色的图像对比度。所有ROI均观察到指数单组分衰减，平均T值范围为0.33至0.45ms，与先前报道的胫骨中段皮质骨T值基本一致。
3D IR-UTE-Cones序列允许使用临床3T扫描仪对髋部皮质骨进行体内容积成像和定量T测量。
