Eun Jung Nam, Choi Yoo Duk, Lee Jeong Ho, Jeong Yun Ah, Yoon Jee Hee, Kim Hee Kyung, Kang Ho-Cheol
Department of Internal Medicine, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Korea.
Department of Pathology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Korea.
Intern Med. 2017;56(14):1839-1842. doi: 10.2169/internalmedicine.56.7884. Epub 2017 Jul 15.
Hypocalcemia is relatively uncommon paraneoplastic syndrome. Only one case of hypocalcemia has been reported in a patient with chondrosarcoma. We herein report a case of a 32-year-old woman with metastatic chondrosarcoma with tetany. Her imaging findings revealed multiple calcific metastatic lesions in the lungs, pancreas, left atrium, and pulmonary vein. A laboratory examination showed hypocalcemia with no evidence of any other disease that could induce hypocalcemia. On the basis of the laboratory and clinical findings, we concluded the etiology of her severe hypocalcemia to be excessive calcium consumption by the tumor itself.
低钙血症是一种相对罕见的副肿瘤综合征。仅有1例软骨肉瘤患者出现低钙血症的报道。我们在此报告1例32岁患有转移性软骨肉瘤并伴有手足搐搦的女性病例。她的影像学检查结果显示肺部、胰腺、左心房和肺静脉有多处钙化转移灶。实验室检查显示低钙血症，且无任何其他可导致低钙血症疾病的证据。根据实验室检查和临床发现，我们得出结论，她严重低钙血症的病因是肿瘤自身过度消耗钙。
