Ehara Shigeru, Nishida Jun, Shiraishi Hideo, Yoshioka Hiroshi, Okada Kyoji, Sumiya Hisashi, Takano Hideyuki
Department of Radiology, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka 020-8505, Japan.
Skeletal Radiol. 2007 Sep;36(9):823-7. doi: 10.1007/s00256-007-0303-9. Epub 2007 Apr 17.
The objective was to elucidate clinical and imaging features of skeletal involvement, recurrences, and metastases of extraskeletal myxoid chondrosarcoma.
Included in this series are 4 patients, aged 44 to 65 years, 3 of whom were men and 1 a woman.
The primary lesions were in the thigh (n = 3) and the upper arm (n = 1). Three patients with multiple metastases died of the disease, 2 were considered to have local recurrence in the adjacent bone. Skeletal metastases occurred after lung metastases in 2 cases, and before lung metastases in 1 case. Typical imaging findings are well-defined lesions with no sclerotic margin or matrix mineralization. A slow, but persistent growth is noted on the imaging features.
Although skeletal metastases of chondrosarcoma of bone and soft tissue are rare, myxoid chondrosarcomas, currently classified tumors of uncertain differentiation, rarely metastasize and/or recur in the bones. The imaging features are typically of a localized lesion with cortical disruption or expansion.
旨在阐明骨外黏液样软骨肉瘤骨骼受累、复发及转移的临床和影像学特征。
本系列纳入4例患者，年龄44至65岁，其中3例为男性，1例为女性。
原发灶位于大腿（n = 3）和上臂（n = 1）。3例发生多处转移的患者死于该疾病，2例被认为在相邻骨出现局部复发。2例骨骼转移发生在肺转移之后，1例发生在肺转移之前。典型的影像学表现为边界清晰的病变，无硬化边缘或基质矿化。影像学特征显示生长缓慢但持续。
尽管骨和软组织软骨肉瘤的骨骼转移罕见，但黏液样软骨肉瘤（目前分类为分化不确定的肿瘤）很少在骨骼中发生转移和/或复发。影像学特征通常为伴有皮质破坏或膨胀的局限性病变。
