Wang Kun-Peng, Chen Ju-Peng, Zhang Si-Jie, Lei Yang, Zhong Hua, Chen Shaojin, Zhou Xin-Hong, Hu Zhi-Qiang
Key Laboratory of Eco-chemical Engineering, Ministry of Education, Qingdao University of Science and Technology, Qingdao, 266042, China.
Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Anal Bioanal Chem. 2017 Sep;409(23):5547-5554. doi: 10.1007/s00216-017-0490-8. Epub 2017 Jul 17.
The thiophene-modified rhodamine 6G (GYJ) has been synthesized as a novel chemosensor. The sensor has sufficiently high selectivity and sensitivity for the detection of Fe and Al ions (M) by fluorescence and ultraviolet spectroscopy with a strong ability for anti-interference performance. The binding ratio of M-GYJ complex was determined to be 2:1 according to the Job's plot. The binding constants for Fe and Al were calculated to be 3.91 × 10 and 5.26 × 10 M, respectively. All these unique features made it particularly favorable for cellular imaging applications. The obvious fluorescence microscopy experiments demonstrated that the probes could contribute to the detection of Fe and Al in related cells and biological organs with satisfying resolution. Graphical abstract GYJ has high selectivity and sensitivity for the detection of Fe(III) and Al(III) with the binding ratio of 2:1.
噻吩修饰的罗丹明6G（GYJ）已被合成作为一种新型化学传感器。该传感器通过荧光和紫外光谱法对铁离子和铝离子（M）具有足够高的选择性和灵敏度，具有很强的抗干扰性能。根据Job曲线确定M-GYJ配合物的结合比为2:1。铁和铝的结合常数分别计算为3.91×10和5.26×10 M。所有这些独特的特性使其特别适用于细胞成像应用。明显的荧光显微镜实验表明，该探针能够以令人满意的分辨率检测相关细胞和生物器官中的铁和铝。图形摘要：GYJ对Fe(III)和Al(III)的检测具有高选择性和灵敏度，结合比为2:1。
