Jaski B E, Wijns W, Foulds R, Serruys P W
Br J Clin Pharmacol. 1986 Apr;21(4):393-400. doi: 10.1111/j.1365-2125.1986.tb05213.x.
Dopexamine increases inotropic state and rate of relaxation independent of changes in heart rate. Dopexamine has a chronotropic effect and results in a decrease in systemic vascular resistance. Dopexamine has a spectrum of action that should be useful in patients with severe heart failure.
多培沙明可增加心肌收缩力和舒张速率,且与心率变化无关。多培沙明具有变时性作用,可导致全身血管阻力降低。多培沙明的一系列作用对重度心力衰竭患者应是有益的。