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多巴胺、多巴酚丁胺和多培沙明对肾血流量影响的比较:一项在正常健康志愿者中的研究。

Comparison of the effects of dopamine, dobutamine, and dopexamine upon renal blood flow: a study in normal healthy volunteers.

作者信息

Mousdale S, Clyburn P A, Mackie A M, Groves N D, Rosen M

机构信息

Department of Anaesthetics, University Hospital of Wales, Heath Park, Cardiff.

出版信息

Br J Clin Pharmacol. 1988 May;25(5):555-60. doi: 10.1111/j.1365-2125.1988.tb03345.x.

Abstract
  1. We compared the effects of dopexamine, dopamine and dobutamine on the heart rate, blood pressure and renal blood flow of six healthy volunteers in an open triple crossover trial. 2. The results suggest that at the dose ranges investigated dopamine was the most effective agent for increasing renal blood flow.
摘要
  1. 在一项开放性三交叉试验中,我们比较了多培沙明、多巴胺和多巴酚丁胺对6名健康志愿者心率、血压和肾血流量的影响。2. 结果表明,在所研究的剂量范围内,多巴胺是增加肾血流量最有效的药物。

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本文引用的文献

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Serial measurement of renal plasma flow.
Eur J Nucl Med. 1985;11(1):33-5. doi: 10.1007/BF00440958.
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The effects of dopexamine on the cardiovascular system of the dog.多培沙明对犬心血管系统的影响。
Br J Pharmacol. 1985 Jul;85(3):609-19. doi: 10.1111/j.1476-5381.1985.tb10555.x.
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Short-term haemodynamic effects of dopexamine in patients with chronic congestive heart failure.
Eur Heart J. 1986 Aug;7(8):697-703. doi: 10.1093/oxfordjournals.eurheartj.a062125.
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Vasodilator therapy of cardiac failure (second of two parts).
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