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多巴胺、多巴酚丁胺和多培沙明对肾血流量影响的比较:一项在正常健康志愿者中的研究。

Comparison of the effects of dopamine, dobutamine, and dopexamine upon renal blood flow: a study in normal healthy volunteers.

作者信息

Mousdale S, Clyburn P A, Mackie A M, Groves N D, Rosen M

机构信息

Department of Anaesthetics, University Hospital of Wales, Heath Park, Cardiff.

出版信息

Br J Clin Pharmacol. 1988 May;25(5):555-60. doi: 10.1111/j.1365-2125.1988.tb03345.x.

DOI:10.1111/j.1365-2125.1988.tb03345.x
PMID:3408636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1386428/
Abstract
  1. We compared the effects of dopexamine, dopamine and dobutamine on the heart rate, blood pressure and renal blood flow of six healthy volunteers in an open triple crossover trial. 2. The results suggest that at the dose ranges investigated dopamine was the most effective agent for increasing renal blood flow.
摘要
  1. 在一项开放性三交叉试验中,我们比较了多培沙明、多巴胺和多巴酚丁胺对6名健康志愿者心率、血压和肾血流量的影响。2. 结果表明,在所研究的剂量范围内,多巴胺是增加肾血流量最有效的药物。

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引用本文的文献

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Use of inotropes and vasopressor agents in critically ill patients.危重症患者中使用正性肌力药和血管加压药。
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Circulatory and diuretic effects of dopexamine infusion in low-birth-weight infants with respiratory failure.多巴酚丁胺输注对低体重呼吸衰竭婴儿的循环及利尿作用
Intensive Care Med. 1996 Jan;22(1):65-70. doi: 10.1007/BF01728334.
3
Vasodilator responses to dopamine in rat perfused mesentery are age-dependent.大鼠肠系膜灌注实验中,多巴胺引起的血管舒张反应具有年龄依赖性。
Br J Pharmacol. 1989 Sep;98(1):302-8. doi: 10.1111/j.1476-5381.1989.tb16895.x.
4
Dopexamine hydrochloride. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in acute cardiac insufficiency.盐酸多培沙明。其药效学和药代动力学特性以及在急性心脏功能不全中的治疗潜力综述。
Drugs. 1990 Feb;39(2):308-30. doi: 10.2165/00003495-199039020-00009.
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Renal effect of dopexamine hydrochloride in patients with chronic renal dysfunction.
Urol Res. 1992;20(6):419-24. doi: 10.1007/BF00294499.

本文引用的文献

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Comparison of measurement of effective renal plasma flow by single plasma sample and plasma disappearance slope/volume methods.
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The haemodynamic and myocardial effects of dopexamine: a new beta 2-adrenoceptor and dopaminergic agonist.多培沙明的血流动力学及心肌效应:一种新型β2肾上腺素能及多巴胺能激动剂
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