Reynolds Michael, Kelly David A, Walker Nicholas J, Crantford Clayton, Defranzo Anthony J
1 Wake Forest Baptist Health, Winston-Salem, NC, USA.
Hand (N Y). 2018 Jan;13(1):74-79. doi: 10.1177/1558944717692090. Epub 2017 Feb 14.
Despite extensive use of Integra in burn reconstruction, little has been published regarding its utility in complex hand wounds from nonburn trauma or cancer resection. This study aimed to review outcomes following Integra use for hand reconstruction following cancer resection or nonburn trauma with exposed bone, joints, and/or tendons.
Retrospective review was performed of patients undergoing hand reconstruction with Integra for exposed bones, joints, or tendons over a 6-year period at a single institution.
Fourteen patients underwent hand reconstruction using Integra, 8 following cancer resection and 6 following acute nonburn trauma. The mean defect size was 19 cm, 79% had exposed tendon without peritenon, 43% had exposed bone without periosteum, and 28% had exposed joint capsule. Mean time from Integra to skin graft was 11.3 days, and negative-pressure wound therapy did not significantly decrease the mean time from Integra to skin graft placement ( P = .76). Overall, 13 patients achieved successful reconstruction with mean skin graft take of 97%, and 1 required revision amputation at the proximal interphalangeal (PIP) joint. Six months postoperative, 92% patients had return of preoperative hand function. Without any surgical revision, 85% of patients were extremely satisfied with the aesthetic result and 15% were fairly satisfied.
Integra is an effective method to treat complex hand wounds with exposed bone, joints, and/or tendons. This technique can be used in the office, lessens the need for local or free flap coverage, and provides an excellent aesthetic outcome. Integra should be considered a viable option in hand reconstruction algorithm.
尽管Integra在烧伤重建中得到广泛应用,但关于其在非烧伤创伤或癌症切除所致复杂手部伤口中的应用报道较少。本研究旨在回顾Integra用于癌症切除或非烧伤创伤后伴有暴露骨骼、关节和/或肌腱的手部重建后的效果。
对在单一机构6年期间接受Integra重建手部暴露骨骼、关节或肌腱的患者进行回顾性研究。
14例患者接受了Integra手部重建,其中8例为癌症切除术后,6例为急性非烧伤创伤后。平均缺损面积为19平方厘米,79%的患者肌腱暴露且无腱周组织,43%的患者骨骼暴露且无骨膜,28%的患者关节囊暴露。从应用Integra到植皮的平均时间为11.3天,负压伤口治疗并未显著缩短从应用Integra到植皮的平均时间(P = 0.76)。总体而言,13例患者成功重建,平均植皮成活率为97%,1例患者需要在近端指间关节进行翻修截肢。术后6个月,92%的患者手部功能恢复至术前水平。未经任何手术翻修,85%的患者对美学效果极为满意,15%的患者较为满意。
Integra是治疗伴有暴露骨骼、关节和/或肌腱的复杂手部伤口的有效方法。该技术可在门诊使用,减少了局部或游离皮瓣覆盖的需求,并提供了出色的美学效果。在手部重建方案中,Integra应被视为一种可行的选择。